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DNA methylation insulates exons from CTCF loops with nuclear speckles (HiChIP)

ABSTRACT: DNA methylation insulates exons from CTCF loops with nuclear speckles (HiChIP)

PROVIDER: PRJNA900272 | ENA |

REPOSITORIES: ENA

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Dataset's files

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			Action	DRS
	SRR22257452_1.fastq.gz	Fastqsanger.gz
	SRR22257452_2.fastq.gz	Fastqsanger.gz
	SRR22257453_1.fastq.gz	Fastqsanger.gz
	SRR22257453_2.fastq.gz	Fastqsanger.gz
	SRR22257454_1.fastq.gz	Fastqsanger.gz

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DNA methylation insulates exons from CTCF loops with nuclear speckles (HiChIP)

Project description:CTCF is necessary for the formation and maintenance of many DNA loops and Topologically Associating Domains, but the genomic features that influence CTCF looping are incompletely understood. We characterized the downstream effects of treating cells with a DNMT1 inhibitor and acute depletion of nuclear speckles to study the factors that influence CTCF looping.

2024-11-11 | GSE217754 | GEO