Streptomyces lividans strain:TK24 YA 8 DG2-P41
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ABSTRACT:
PROVIDER: PRJNA902010 | ENA |
REPOSITORIES: ENA
Similar Datasets
Project description:Streptomyces lividans TK24 DG2-P41 Genome sequencing
| PRJNA694176 | ENA
Project description:Comparative genomic hybridization analysis of Streptomyces coelicolor A3(2) versus Streptomyces lividans 66 and Streptomyces lividans TK24 using high density 105,000 x 60-mer ink-jet in situ synthesized arrays.
2011-10-01 | E-MAXD-58 | biostudies-arrayexpress
Project description:Streptomyces lividans TK24 Proteome
| PRJNA952857 | ENA
Project description:Streptomyces lividans TK24 Genome sequencing
| PRJNA257077 | ENA
Project description:By the direct comparison of illuminated and non-illuminated microtiter plate cultures of Streptomyces lividans TK24 transcriptomes, the effects of differing cultivation systems by the relevance of light, a parameter that is usually out of scope during heterotrophic bioprocesses, could be addressed.
2017-05-01 | E-MTAB-5623 | biostudies-arrayexpress
Project description:When SCO0988 was overexpressed in Streptomyces lividans TK24, it reveals the mechanism of acetyltransferase SCO0988 on regulating secondary metabolism by comparing acetylome of overexpressed strains and control strains
2023-04-14 | PXD041540 |
Project description:Transcriptome study of Streptomyces lividans TK24 and the derivative strain, TK24 Delta-ftsH Raw sequence reads
| PRJNA454576 | ENA
Project description:The gene aml encoding alpha-amylase in Streptomyces lividans was cloned in the multicopy plasmid pIJ486, generating plasmid pAMI11. Plasmid pAMI11 and pIJ486 were propagated in S. lividans TK21 to obtain S. lividans TK21(pAMI11) and its isogenic strain S. lividans TK21(pIJ486). Transcriptional profiling of the bacterium that overproduces alpha-amylase mainly resulted in the upregulation of genes involved in the biogenesis and function of ribosomes, together with the upregulation of the genes involved in the redox processes, the ABC transporters, the central carbon, aminoacid and purine /pyrimidine metabolism. Moreover, some genes involved in oxidative stress were upregulated. The number of genes downregulated was much lower than the upregulated ones. Therefore, bacteria respond by favouring alpha-amylase overproduction that apparently does not cause damage to the cell.
2015-07-23 | GSE61448 | GEO
Project description:The Streptomyces lividans lsp gene encodes a type II signal peptidase (Lsp) that cleaves the type II leader peptides of lipoproteins. Transcriptional profiling of the bacterium depleted of the lsp gene mainly resulted in deactivation of the sigma U regulon, as well as in downregulation of genes involved in the biogenesis and function of ribosomes and genes encoding some major secretory proteins as determined by hybridisation of commercially available S. lividans genome-wide microarrays. Almost 50% of the dowregulated genes have been described as forming part of the stringent response in streptomycetes. The gene encoding the S. lividans extracellular foldase, the lipoprotein FkpA, is equally downregulated. Therefore, the deletion of lsp from the S. livdans genome temporarily triggers a cellular stress where the stringent response is, at least, partially induced.
2014-05-22 | GSE30728 | GEO
Project description:The gene dagA encoding agarase in Streptomyces coelicolor was cloned in the multicopy plasmid pIJ486 generating plasmid pAGAs5. Plasmid pAGAs5 and pIJ486 were propagated in S. lividans TK21 to obtain S. lividans TK21(pAGAs5) and its isogenic strain S. lividans TK21(pIJ486). Transcriptional profiling of the bacterium that overproduces agarase mainly resulted in the downregulation of the genes involved in the biogenesis and function of ribosomes, together with the downregulation of the genes involved in nitrogen, aminoacids, purine/pyrimidine and central carbon metabolism as well as ABC transporters, redox processes and fatty acids biosynthesis. The number of genes upregulated in the agarase overproducer strain is lower than in the downregulated ones. Almost 50% of the dowregulated genes have been described as forming part of the stringent response in streptomycetes. Therefore, the overproduction of agarase may lead to a condition of nutrient depletion that triggers the stringent response.
2015-07-23 | GSE61447 | GEO