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Gene expression profile at single cell level of bulk liver allograft tissue isolated 12 months post-transplant in patients receiving regulatory dendritic cell therapy (STUDY) and reference standard-of-care patients (SOC)

ABSTRACT: Gene expression profile at single cell level of bulk liver allograft tissue isolated 12 months post-transplant in patients receiving regulatory dendritic cell therapy (STUDY) and reference standard-of-care patients (SOC)

PROVIDER: PRJNA902375 | ENA |

REPOSITORIES: ENA

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			Action	DRS
	SRR22313879.fastq.gz	Fastqsanger.gz
	SRR22313880.fastq.gz	Fastqsanger.gz
	SRR22313881.fastq.gz	Fastqsanger.gz
	SRR22313882.fastq.gz	Fastqsanger.gz
	SRR22313883.fastq.gz	Fastqsanger.gz

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Gene expression profile at single cell level of bulk liver allograft tissue isolated 12 months post-transplant in patients receiving regulatory dendritic cell therapy (STUDY) and reference standard-of-care patients (SOC)

Project description:Regulatory dendritic cell therapy has shown potential in modulating the effector immune response after liver transplant in precliical models . We used single cell RNA sequencing (scRNA-seq) to analyze the differences in immune cell landscape of liver allograft at 12 months post-transplant in patients infused with regulatory dendritic cell therapy compared to standard-of-care control patients.

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