Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Effect of radiation therapy on gene expression of different murine cardiac cell lineage at different time points post radiation [RNA-seq]

ABSTRACT: Effect of radiation therapy on gene expression of different murine cardiac cell lineage at different time points post radiation [RNA-seq]

PROVIDER: PRJNA903877 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR22356915_1.fastq.gz	Fastqsanger.gz
	SRR22356915_2.fastq.gz	Fastqsanger.gz
	SRR22356916_1.fastq.gz	Fastqsanger.gz
	SRR22356916_2.fastq.gz	Fastqsanger.gz
	SRR22356917_1.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 84

Similar Datasets

Effect of radiation therapy on gene expression of different murine cardiac cell lineage at different time points post radiation [RNA-seq]

Project description:To investigate the pathways affected by radiation at the cellular levels in the heart, we radiated WT mice with 12 Gyx1 RT and isolated constituents cell lineages We then performed gene expression profiling analysis using data obtained from RNA-seq of endothelial cells, fibroblasts and myocytes at 3 different time points

2022-12-09 | GSE218447 | GEO

Analysis of gene co-expression networks in skin cells exposed to different doses of ionising radiation at different time points

Project description:Most studies have analysed the effects of high dose radiation such as atomic bomb survivors in Japan, people exposed during the Chernobyl nuclear accident, patients undergoing radiation therapy, uranium miners, etc. However, it has been difficult to measure and assess the risk of cancer in people exposed to lower doses of ionising radiation, such as the people living at high altitudes, who are exposed to more natural background radiation from cosmic rays than people at sea level. We measured the genomic response to X-ray ionising radiation (10 cGy and 100 cGy) in a skin tissue model to compare the effects of low and high dose ionising radiation at different time points. The microarray data was then analysed using state-of-the art “upside-down pyramid” computational systems biology methods to identify genes contributing to the difference in the response to the different radiation doses.

2012-02-01 | GSE29344 | GEO

Analysis of gene co-expression networks in skin cells exposed to different doses of ionising radiation at different time points

2012-02-01 | E-GEOD-29344 | biostudies-arrayexpress

Sequencing of Caenorhabditis elegans at 4 different time points

Project description:Sequencing of Caenorhabditis elegans at 4 different time points

| PRJNA434698 | ENA

24 chemicals exposure to hESCs at different doses and time points

Project description:24 chemicals exposure to hESCs at different doses and time points

| PRJNA777904 | ENA

ATACseq samples of Arabidopsis thaliana regenerating root at different time points.

Project description:ATACseq samples of Arabidopsis thaliana regenerating root at different time points.

| PRJNA707061 | ENA

RNA sequencing on cardiac fibroblasts harvested at different time points following induction of osteogenic differentiation

Project description:Purpose: To analyze cardiac fibroblasts gene expression at different time following induction of osteogenic differentiation Methods: Freshly isolated cardiac fibroblasts (Passage 0 or passage 1) were plated at a density of 2.5 x 104 cells/cm2 in growth medium. After overnight incubation, osteogenesis was induced using differentiation medium (α-MEM supplemented with 10% FBS, 10 nM dexamethasone (Sigma, D4902), 20 mM β-glycerol phosphate (Sigma, G9422), and 50 μM L-ascorbic acid (Sigma, A4403). Cardiac fibroblasts harvested at Day0 (before differentiation medium treatment), Day7, Day14 and Day21 were used for RNA sequencing. Results: Cardiac fibroblasts harvested at different time points following induction of differentiation revealed clusters of genes whose expression was significantly altered in a temporal specific manner. Genes regulating cell cycle that were highly expressed in undifferentiated cardiac fibroblasts were down-regulated at the onset of differentiation and remained at low expression levels throughout the duration of osteogenic differentiation, consistent with the principle that induction of differentiation is associated with reduced rates of proliferation. In contrast, genes that were minimally expressed in cardiac fibroblasts were induced in a specific temporal manner during the course of osteogenic differentiation and included sets of genes known to regulate inflammation, extracellular matrix proteins and cell metabolism. Conclusions: Cardiac fibroblasts subjected to osteogenic differentiation progressively adopted an osteogenic signature.

2016-11-07 | GSE87836 | GEO

Genomic profile of fatigued men receiving localized radiation therapy

Project description:Microarray gene expression of peripheral blood of the prostate cancer patients receiving localized external beam radiation therapy (EBRT) Assay processed at EBRT time points, baseline, midpoint (days 19-21) and endpoint (days 38-42)

2015-06-17 | GSE69961 | GEO

RNA-seq of mouse wounds from different time points, treatment and genotype

Project description:RNA-seq of mouse wounds from different time points, treatment and genotype

| PRJEB59493 | ENA

Wild-type, Foxa2-/-, and Nkx2.2-/- mESCs at different time points of differentiation

Project description:Wild-type, Foxa2-/-, and Nkx2.2-/- mESCs at different time points of differentiation

| PRJNA784960 | ENA