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Suclg2 maintains the tolerogenic function of regulatory dendritic cells by suppressing Lactb succinylation

ABSTRACT: Suclg2 maintains the tolerogenic function of regulatory dendritic cells by suppressing Lactb succinylation

PROVIDER: PRJNA906581 | ENA |

REPOSITORIES: ENA

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Suclg2 maintains the tolerogenic function of regulatory dendritic cells by suppressing Lactb succinylation [si-nc/si-Suclg2]

Project description:Suclg2 maintains the tolerogenic function of regulatory dendritic cells by suppressing Lactb succinylation [si-nc/si-Suclg2]

| PRJNA908261 | ENA

Suclg2 maintains the tolerogenic function of regulatory dendritic cells by suppressing Lactb succinylation

Project description:Purpose: mRNAs sequencing of the gene expression differences in maDC and diffDC, the goals of this study are to investigate the biological effect of the metabolic enzyme succinate-CoA ligase subunit beta Suclg2 in regulating regulatory DC differentiation and function.

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Suclg2 maintains the tolerogenic function of regulatory dendritic cells by suppressing Lactb succinylation [si-nc/si-Suclg2]

Project description:Purpose: mRNAs sequencing of the gene expression differences in diffDC transfected with si-nc or si-Suclg2, the goals of this study are to investigate the biological effect of the metabolic enzyme succinate-CoA ligase subunit beta Suclg2 in regulating regulatory DC differentiation and function.

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As an unfavorable prognostic factor, LACTB promotes metastasis of nasopharyngeal carcinoma via activation of ERBB3/EGFR-ERK signaling

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Gene expression in tolerogenic TGFb-treated macrophages

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