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Gene expression analysis of hESCs undergoing neuronal differentiation exposed to paracetamol [RNA-seq]

ABSTRACT: Gene expression analysis of hESCs undergoing neuronal differentiation exposed to paracetamol [RNA-seq]

PROVIDER: PRJNA908093 | ENA |

REPOSITORIES: ENA

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Gene expression analysis of hESCs undergoing neuronal differentiation exposed to paracetamol [RNA-seq]

Project description:Genome-wide gene expression profiling of hESCs undergoing neuronal differentiation at four distinct time-points. hESCs are differentiated using a neuronal differentiation protocol, day 7 and 20 were charachterized. Cells were exposed to 100 or 200 μM paracetamol from Day 1 were charachterised at Day 7 and Day 20.

2023-08-31 | GSE220024 | GEO

Single-cell ATAC-seq analysis of hESCs undergoing neuronal differentiation exposed to paracetamol [scATAC-seq]

Project description:Genome-wide chromatin opening profiling of hESCs undergoing neuronal differentiation at four distinct time-points. hESCs are differentiated using a neuronal protocol, and day 20 were charachterized. Cells exposed to 100 or 200 μM paracetamol from Day 1.

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Single-cell gene expression analysis of hESCs undergoing neuronal differentiation upon exposure to paracetamol [scRNA-seq]

Project description:Single-cell RNA-seq of hESCs undergoing neuronal differentiation at four distinct time-points. hESCs are differentiated using a novel protocol, and day 0, 7, 13 and 20 were charachterized. Cells exposed to 100 or 200 μM paracetamol from Day 1 were charachterised at Day 7 and Day 20.

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Epigenome analysis of hESCs undergoing neuronal differentiation in presence or absence of paracetamol [MethylationEPIC BeadChip]

Project description:Genome wide DNA methylation profiling of human embryonic stem cells (hESCs) at day 0, and day 7, 13 and 20 of neuronal differentiation. Cells were exposed to paracetamol from Day 1 and onwards. The Illumina Infinium MethylationEPIC_v-1-0_B3 was used to obtain DNA methylation profiles accross approximately 850k CpGs in differentiating cells.

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Single-cell ATAC-seq analysis of hESCs undergoing neuronal differentiation exposed to paracetamol [scATAC-seq]

Project description:Single-cell ATAC-seq analysis of hESCs undergoing neuronal differentiation exposed to paracetamol [scATAC-seq]

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Gene expression analysis of hESCs undergoing neuronal differentiation exposed to citalopram

Project description:Genome-wide gene expression profiling of human embryonic stem cells (hESCs) undergoing neuronal differentiation at four distinct time-points. hESCs are differentiated towards neuronal cells for 13 days, and sampled for downstream analysis at day 0, 6, 10 and 13 . Cells exposed to 50, 100, 200 and 400 nM citalopram from Day 1 were charachterised at Day 6, 10 and 13.

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Gene expression analysis of hESCs undergoing neuronal differentiation exposed to citalopram

Project description:Gene expression analysis of hESCs undergoing neuronal differentiation exposed to citalopram

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Epigenome analysis of hESCs undergoing neuronal differentiation

Project description:Genome wide DNA methylation profiling of human embryonic stem cells of hESCs undergoing neuronal differentiation at four distinct time-points. hESCs are differentiated towards neuronal cells for 13 days, and sampled for downstream analysis at day 0, 6, 10 and 13 . Cells exposed to 50, 100, 200 and 400 nM citalopram from Day 1 were charachterised at Day 6, 10 and 13. The Illumina Infinium MethylationEPIC_v-1-0_B3 was used to obtain DNA methylation profiles accross approximately 850k CpGs in differentiating cells.

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Epigenome analysis of hESCs undergoing neuronal differentiation in presence or absence of paracetamol [MethylationEPIC BeadChip]

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Single cell gene expression analysis of hESCs undergoing neuronal differentiation

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