Project description:Intra- and extracellular metabolomics dataset of human dermal blood endothelial cells (HDBECs), human umbilical vein endothelial cells (HUVECs), human dermal lymphatic endothelial cells (HDLECs) and intestinal lymphatic endothelial cells (iLECs) in proliferation and quiescence.
Project description:Primary human umbilical vein endothelial cells (HUVECs, n=4) were exposed to low-magnitude pre-conditioning FSS (1.5 dynes/cm2) 18h using the Ibidi pump system followed by exposure to the arterial- (15 dynes/cm2) or venous-magnitude (1.5 dynes/cm2) FSS for 24h. Conditioned media was collected to analyse the effect of acute changes in the haemodynamic environment on the EC secretome.