Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Muribaculum intestinale

ABSTRACT: Muribaculum intestinale Metagenomic assembly

PROVIDER: PRJNA910981 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR22681855_1.fastq.gz	Fastqsanger.gz
	SRR22681855_2.fastq.gz	Fastqsanger.gz

Items per page:

1 - 2 of 2

Similar Datasets

Muribaculum intestinale

Project description:Muribaculum intestinale Genome sequencing and assembly

| PRJNA506121 | ENA

Muribaculum intestinale

Project description:Muribaculum intestinale Genome sequencing and assembly

| PRJNA506127 | ENA

Muribaculum intestinale strain:DSM 100739

Project description:Muribaculum intestinale strain:DSM 100739 Genome sequencing and assembly

| PRJNA434638 | ENA

Muribaculum intestinale strain:DSM 100746

Project description:Muribaculum intestinale strain:DSM 100746 Genome sequencing and assembly

| PRJNA434640 | ENA

Muribaculum sp.

Project description:Muribaculum sp. Genome sequencing and assembly

| PRJNA524751 | ENA

A Cardiolipin from <i>Muribaculum intestinale</i> Induces Antigen-Specific Cytokine Responses.

Project description:An systematic phenotypic screen of the mouse gut microbiome for metabolites with an immunomodulatory effect identified Muribaculum intestinale as one of only two members with an oversized effect on T-cell populations. Here we report the identification and characterization of a lipid, MiCL-1, as the responsible metabolite. MiCL-1 is an 18:1-16:0 cardiolipin, whose close relatives are found on concave lipid surfaces of both mammals and bacteria. MiCL-1 was synthesized to confirm the structural analysis and functionally characterized in cell-based assays. It has a highly restrictive structure-activity profile, as its chain-switched analog fails to induce responses in any of our assays. MiCL-1 robustly induces the production of pro-inflammatory cytokines like TNF-α, IL-6, and IL-23, but has no detectable effect on the anti-inflammatory cytokine IL-10. As is the case with other recently discovered immunomodulatory lipids, MiCL-1 requires functional TLR2 and TLR1 but not TLR6 in cell-based assays.

| S-EPMC10623554 | biostudies-literature

Amedibacterium intestinale

Project description:Amedibacterium intestinale overview

| PRJNA644980 | ENA

Paramuribaculum intestinale

Project description:Paramuribaculum intestinale overview

| PRJNA855511 | ENA

Clostridium intestinale

Project description:Clostridium intestinale overview

| PRJNA189569 | ENA

Clostridium intestinale URNW

Project description:Clostridium intestinale URNW Genome sequencing and assembly