Project description:In this study, we firstly obtained the complete mitochondrial genome DNA sequence of the Ambassis gymnocephalus. Its length is 17,388 bp, containing 13 protein-coding genes, 2 rRNAs, 22 tRNAs and a large noncoding region. The overall length of protein coding genes is 11,448 bp, including A (26.75%), G (15.20%), T (26.44%) and C (31.61%). The A + T content of control region (1555 bp) is 60.45%. The protein-coding gene COI is started by GTG and ended by AGA. From the phylogenetic tree, we find A. gymnocephalus and Oreochromis niloticus has the closest relationship among 21 related species. This work will provide some valuable information for further studies on A. gymnocephalus and the family Ambassidae.
Project description:The DNA isolated from 44 either frozen or FFPE Neuroendocrine Neoplasm (NEN) was analysed by NGS, to identify genes more likely to be subject to sequence variations among 523 cancer-related ones.
Project description:Plasma DNA from 558 malignancies, 263 benign and borderline tumors and 367 healthy control samples were collected and subjected to random short-gun whole genome sequencing.
