Project description:Transcriptional profiling of Bartonella quintana grown on a plate at 28C and 37C for various time points. Comparing each individual sample in cy5 to a pooled mix of all samples in cy3 to preserve a common denominator.

2012-12-05 | E-GEOD-42685 | biostudies-arrayexpress

Shortgun Proteomic analysis of two Bartonella quintana strains

Project description:Proteomic analysis two strains of Bartonella quintana using In-solution digestion followed by Stron Cation Exchange (SCX) and RP nano-LC-MS/MS

2013-06-03 | PXD000076 | Pride

Bartonella quintana

Project description:Bartonella quintana: growth phase and temperature response

| PRJNA182947 | ENA

Bartonella quintana strain:MF1-1

Project description:Macaque-derived Bartonella quintana strains

| PRJDB8098 | ENA

Mapping the tRNA Modification Landscape of Bartonella henselae Houston I and Bartonella quintana Toulouse

Project description:Transfer RNA (tRNA) modifications play a crucial role in maintaining translational fidelity and efficiency, and they may function as regulatory elements in stress response and virulence. Despite their pivotal roles, a comprehensive mapping of tRNA modifications and their associated synthesis genes is still limited, with a predominant focus on free-living bacteria. In this study, we employed a multidisciplinary approach, incorporating comparative genomics, mass spectrometry, and next-generation sequencing, to predict the set of tRNA modification genes responsible for tRNA maturation in two intracellular pathogens—Bartonella henselae Houston I and Bartonella quintana Toulouse, which are causative agents of cat-scratch disease and trench fever, respectively. This analysis presented challenges, particularly because of host RNA contamination, which served as a potential source of error. However, our approach predicted 26 genes responsible for synthesizing 23 distinct tRNA modifications in B. henselae and 22 genes associated with 23 modifications in B. quintana. Notably, akin to other intracellular and symbiotic bacteria, both Bartonella species have undergone substantial reductions in tRNA modification genes, mostly by simplifying the hypermodifications present at positions 34 and 37. B. quintana exhibited the additional loss of four modifications and these were linked to examples of gene decay, providing snapshots of reductive evolution.

2024-01-23 | PXD048805 | Pride

Bartonella quintana RM-11 strain:RM_11

Project description:Bartonella quintana RM-11 strain:RM_11 Genome sequencing

| PRJNA173218 | ENA

Shortgun Proteomic analysis of two Bartonella quintana strains

Project description:Proteomic analysis two strains of Bartonella quintana using In-solution digestion followed by Stron Cation Exchange (SCX) and RP nano-LC-MS/MS

| MSV000079310 | MassIVE

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