Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Self-Organized Generation Of Hepatic Cord Like Organoids (HCLOs) With Zonal Diversity (RNA-seq)

ABSTRACT: Self-Organized Generation Of Hepatic Cord Like Organoids (HCLOs) With Zonal Diversity (RNA-seq)

PROVIDER: PRJNA922949 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR23049690_1.fastq.gz	Fastqsanger.gz
	SRR23049690_2.fastq.gz	Fastqsanger.gz
	SRR23049691_1.fastq.gz	Fastqsanger.gz
	SRR23049691_2.fastq.gz	Fastqsanger.gz
	SRR23049692_1.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 18

Similar Datasets

Self-Organized Generation Of Hepatic Cord Like Organoids (HCLOs) With Zonal Diversity

Project description:Self-Organized Generation Of Hepatic Cord Like Organoids (HCLOs) With Zonal Diversity

| PRJNA922964 | ENA

Self-Organized Generation Of Hepatic Cord Like Organoids (HCLOs) With Zonal Diversity (snRNAseq)

Project description:Self-Organized Generation Of Hepatic Cord Like Organoids (HCLOs) With Zonal Diversity (snRNAseq)

| PRJNA922963 | ENA

Self-Organized Generation Of Hepatic Cord Like Organoids (HCLOs) With Zonal Diversity (ChIPseq)

Project description:Self-Organized Generation Of Hepatic Cord Like Organoids (HCLOs) With Zonal Diversity (ChIPseq)

| PRJNA922973 | ENA

Self-Organized Generation Of Hepatic Cord Like Organoids (HCLOs) With Zonal Diversity (ChIPseq)

Project description:To investigate the efect of extracellular bilirubin and intracellular ascorbate on the development of zonal hepatocytes in human liver organoids.

2024-09-18 | GSE222653 | GEO

Self-Organized Generation Of Hepatic Cord Like Organoids (HCLOs) With Zonal Diversity (snRNAseq)

Project description:To investigate the efect of extracellular bilirubin and intracellular ascorbate on the development of zonal hepatocytes in human liver organoids.

2024-09-18 | GSE222648 | GEO

Self-Organized Generation Of Hepatic Cord Like Organoids (HCLOs) With Zonal Diversity (RNA-seq)

Project description:To investigate the efect of extracellular bilirubin and intracellular ascorbate on the development of zonal hepatocytes in human liver organoids

2024-09-18 | GSE222641 | GEO

Self-Organized Generation Of Hepatic Cord Like Organoids (HCLOs) With Zonal Diversity

Project description:This SuperSeries is composed of the SubSeries listed below.

2024-09-18 | GSE222654 | GEO

Self-organized emergence of hyaline cartilage in hiPSC-derived multi-tissue organoids

Project description:Self-organized emergence of hyaline cartilage in hiPSC-derived multi-tissue organoids

| PRJNA762700 | ENA

Self-organized emergence of hyaline cartilage in hiPSC-derived multi-tissue organoids

Project description:Here, we developed a simple xeno- and feeder-free protocol for human hyaline cartilage production in vitro using hydrogel-cultured multi-tissue organoids (MTO). We investigate gene regulatory networks during spontaneous hiPSC-MTO differentiation using RNA sequencing and bioinformatic analyses. We find the interplays between BMPs and neural FGF pathways are associated with MTO phenotype transition. We recognize TGF-beta/BMP and Wnt signaling likely contribute to the long-term maintenance of cartilage growth and specific increase in articular cartilage development. By comparing MTO cartilage transcription signature with human lower limb chondrocytes, we observe MTO chondrocytes show strong correlation with fetal lower limb cartilage tissues. Collectively, our findings describe self-organized emergence of MTO hyaline cartilage, its associated molecular pathways, and spontaneous adoption of articular cartilage development trajectories by MTO.

2022-09-12 | GSE184007 | GEO

Self-organized trunk-like-structures with somites and a neural tube

Project description:Self-organized trunk-like-structures with somites and a neural tube

| PRJNA592534 | ENA