Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Differential binding of PARP-1 domains

ABSTRACT: Differential binding of PARP-1 domains

PROVIDER: PRJNA923684 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR23077603_1.fastq.gz	Fastqsanger.gz
	SRR23077603_2.fastq.gz	Fastqsanger.gz
	SRR23077604_1.fastq.gz	Fastqsanger.gz
	SRR23077604_2.fastq.gz	Fastqsanger.gz
	SRR23077605_1.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 48

Similar Datasets

Differential binding of PARP-1 domains (ZNII-YFP ChIP-seq)

Project description:We interrogated the differential binding of PARP-1 domains (ZnI, ZnII, AD-WGR) and a ZnI mutant in Drosophila via ChIP-seq of third-instar larvae.

2023-05-25 | GSE222875 | GEO

Differential binding of PARP-1 domains (ZNI-YFP ChIP-seq)

Project description:We interrogated the differential binding of PARP-1 domains (ZnI, ZnII, AD-WGR) and a ZnI mutant in Drosophila via ChIP-seq of third-instar larvae.

2023-05-25 | GSE222873 | GEO

Differential binding of PARP-1 domains (AW-YFP ChIP-seq)

Project description:We interrogated the differential binding of PARP-1 domains (ZnI, ZnII, AD-WGR) and a ZnI mutant in Drosophila via ChIP-seq of third-instar larvae.

2023-05-25 | GSE222876 | GEO

Differential binding of PARP-1 domains (DZNI-YFP ChIP-seq)

Project description:We interrogated the differential binding of PARP-1 domains (ZnI, ZnII, AD-WGR) and a ZnI mutant in Drosophila via ChIP-seq of third-instar larvae.

2023-05-25 | GSE222865 | GEO

Differential binding of PARP-1 domains (ZNII-YFP ChIP-seq)

Project description:Differential binding of PARP-1 domains (ZNII-YFP ChIP-seq)

| PRJNA923685 | ENA

Differential binding of PARP-1 domains (ZNI-YFP ChIP-seq)

Project description:Differential binding of PARP-1 domains (ZNI-YFP ChIP-seq)

| PRJNA923687 | ENA

Differential binding of PARP-1 domains (AW-YFP ChIP-seq)

Project description:Differential binding of PARP-1 domains (AW-YFP ChIP-seq)

| PRJNA923692 | ENA

Differential binding of PARP-1 domains (DZNI-YFP ChIP-seq)

Project description:Differential binding of PARP-1 domains (DZNI-YFP ChIP-seq)

| PRJNA923674 | ENA

Differential binding of PARP-1 domains

Project description:This SuperSeries is composed of the SubSeries listed below.

2023-05-25 | GSE222877 | GEO

Depletion of PARP-2 in HepG2 cells

Project description:Poly(ADP-ribose) polymerase-2 (PARP-2) is acknowledged as a DNA repair enzyme; however, recently metabolic properties had been attributed to it. Hereby, we examined the metabolic consequences of PARP-2 ablation in liver. Microarray analysis of PARP-2 knockdown HepG2 cells revealed the dysregulation of lipid and cholesterol metabolism genes. Induction of cholesterol biosynthesis genes stemmed from the enhanced expression of sterol-regulatory element binding protein (SREBP)-1. We revealed that PARP-2 is a suppressor of the SREBP-1 promoter, therefore ablation of PARP-2 induces SREBP-1 expression and consequently cholesterol synthesis. PARP-2-/- mice had higher SREBP-1 expression that was translated into enhanced hepatic and serum cholesterol levels. PARP-2 silencing was performed employing shPARP-2 (small hairpin) and scPARP-2 (scrambled) shRNA by lentiviral delivery (Sigma) using 40 MOI lentiviruses coding shRNA sequence against PARP-2.

2013-12-31 | E-GEOD-43981 | biostudies-arrayexpress

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data