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Epigenetic study on CBP inhibiting differentiation of porcine muscle satellite cells (RNA-Seq)

ABSTRACT: Epigenetic study on CBP inhibiting differentiation of porcine muscle satellite cells (RNA-Seq)

PROVIDER: PRJNA930749 | ENA |

REPOSITORIES: ENA

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Epigenetic study on CBP inhibiting differentiation of porcine muscle satellite cells

Project description:Epigenetic study on CBP inhibiting differentiation of porcine muscle satellite cells

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Epigenetic study on CBP inhibiting differentiation of porcine muscle satellite cells (CUT&Tag)

Project description:Epigenetic study on CBP inhibiting differentiation of porcine muscle satellite cells (CUT&Tag)

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Epigenetic study on CBP inhibiting differentiation of porcine muscle satellite cells (ATAC-Seq)

Project description:Epigenetic study on CBP inhibiting differentiation of porcine muscle satellite cells (ATAC-Seq)

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Epigenetic study on CBP inhibiting differentiation of porcine muscle satellite cells (RNA-Seq)

Project description:These data are transcriptome sequencing data of porcine muscle satellite cells at the stage of proliferation and differentiation.

2024-07-01 | GSE224382 | GEO

Epigenetic study on CBP inhibiting differentiation of porcine muscle satellite cells (ATAC-Seq)

Project description:These data are ATAC-Seq data of porcine muscle satellite cells at the stage of proliferation and differentiation.

2024-07-01 | GSE224380 | GEO

Epigenetic study on CBP inhibiting differentiation of porcine muscle satellite cells (CUT&Tag)

Project description:The data are the cut&tag data sequencing data of H3K4me3, H3K27Ac and H3K27me3 of pig muscle satellite cells at the stage of proliferation and differentiation.

2024-07-01 | GSE224381 | GEO

Epigenetic study on CBP inhibiting differentiation of porcine muscle satellite cells

Project description:This SuperSeries is composed of the SubSeries listed below.

2024-07-01 | GSE224383 | GEO

Gene expression profiling of porcine skeletal muscle satellite cells after challenge with poly I:C

Project description:Porcine satellite cells play a vital role in the construction, development, and self-renewal of skeletal muscle. In this study, porcine satellite cells were exposed to mimic viral infection poly (I:C) during proliferation and differentiation phases at 0h, 12h, 24h and 48h time points. The untreated and treated porcine satellite cells during proliferation and differentiation phases were further analyzed by RNA sequencing technology. In the proliferation and differentiation phases of porcine satellite cells grown under poly (I:C), 88, 119, 104 and 95 genes were differentially expressed in 0h – 12h treated, 12h – 24h treated, 0h – 24h treated and 24h – 48h untreated comparison libraries, respectively. The GO terms analysis results showed that in the proliferation phase of treated porcine satellite cells, the up-regulated genes related to the immune system were highly expressed. In addition, the gene expression associated with muscle structure development, response to growth factor emerged in the differentiation phase of untreated porcine satellite cells. The biological pathways associated with Influenza A, Toll-like signaling as well as chemokine signaling were revealed through poly (I:C) stimulation of porcine satellite cells. The differentially expressed genes were confirmed by quantitative real-time PCR. Our findings expanded the understanding of gene expression and signaling pathways about the infiltrated mechanism of the virus into porcine skeletal muscle satellite cells.

2018-03-31 | GSE112527 | GEO

RNA-seq data of porcine satellite cells at 24h and 36h of differentiation

Project description:We isolated and cultured porcine skeletal muscle satellite cells (PSCs). PSCs were induced to differentiate. At 24h and 36h of differentiation, the PSCs were collected for RNA-seq. Each group had three biological replicates.

2020-12-22 | GSE141648 | GEO

Transcription profiling of mouse satellite cells isolated from skeletal muscle

Project description:(Abstract of publication submitted currently) To clarify molecular regulation of satellite cells, we performed genome-wide gene expression analysis of quiescent satellite cells isolated from mouse skeletal muscle by flow cytometry. We identified 53 novel quiescent satellite cell-specific genes whose expressions are sharply down-regulated upon activation. The gene list contains a number of cell surface molecules, transcriptional factors, and cytokines and other signal transduction molecules. We further confirmed that Odz4 and calcitonin receptor proteins were expressed by quiescent but not by activated satellite cells in vivo. Importantly, we found that Pax7+/calcitonin receptor+ satellite cells reappear in close association with regenerating myofibers 7 days after muscle damage, often outside the basal lamina. Moreover, an agonist of calcitonin receptor suppressed the activation of quiescent satellite cells on myofibers in in vitro culture, suggesting that calcitonin receptor signaling plays an important role in renewal and maintenance of satellite cells. Our results show the gene expression profile of quiescent satellite cells for the first time and reveal the temporal and spatial reappearance of a satellite cell pool. Experiment Overall Design: Satellite cells and non-satellite cells were examined. Totally three types of cells (groups), the satellite cells in quiescent and activated states and the non-satellite cells, were compared. Each has 4 replicates.

2008-06-12 | E-GEOD-3483 | biostudies-arrayexpress

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