Project description:Reverse genetics has been widely used to investigate function of viral genes. In the present study we investigated the gene expression profile of a primary ovine cell (OFTu) in response to infection with the wild type (OV-IA82) and deletion mutant virus (OV-IA82Δ024) aiming to determine possible functions for ORFV024 during ORFV infection. We used microarray analysis to investigate gene expression profile of OFTu with ORFV OV-IA82 and OV-IA82Δ024.
Project description:To find out differently expressed circRNAs during Orf virus infection of GSF cells and their potential roles in response to ORFV infection