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LUTI-dependent Downregulation of a Cell Cycle Transcription Factor is Key for Timely Meiotic Entry

ABSTRACT: LUTI-dependent Downregulation of a Cell Cycle Transcription Factor is Key for Timely Meiotic Entry

PROVIDER: PRJNA938113 | ENA |

REPOSITORIES: ENA

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			Action	DRS
	SRR23602621.fastq.gz	Fastqsanger.gz
	SRR23602622.fastq.gz	Fastqsanger.gz
	SRR23602623.fastq.gz	Fastqsanger.gz
	SRR23602624.fastq.gz	Fastqsanger.gz
	SRR23602625.fastq.gz	Fastqsanger.gz

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LUTI-dependent Downregulation of a Cell Cycle Transcription Factor is Key for Timely Meiotic Entry

Project description:We used RNA-seq to monitor expression of early meiotic genes and expression of mitotic transcription factor SBF targets. Increased SBF activity was achieved through either overexpression of SBF unique subunit Swi4 , removal of LUTI-mediated regulation of Swi4 levels, or nuclear depeletion of negative regulator of SBF Whi5.

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