Project description:This study investigated the transcriptional response of C. elegans after 0, 30, 60, 120, and 480 minutes of ethanol or mock exposure (n=4 per timepoint and treatment). Age synchronized Bristol N2 animals were obtained by allowing fertile adults to lay eggs for 3 hours. After which adults were removed and the population was incubated for 3 days at 20 ˚C. After ethanol exposure, RNA was isolated, labeled and hybridized on Agilent C. elegans (V2) Gene Expression Microarray 4X44K slides.
Project description:Novel roles of C. elegans heterochromatin protein HP1 and linker histone HIS-24 in the regulation of innate immune gene expression and stress Response
