Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Circular RNA hsa_circ_0064559 is identified to affect the progression of colorectal cancer [PrimeView]

ABSTRACT: Circular RNA hsa_circ_0064559 is identified to affect the progression of colorectal cancer [PrimeView]

PROVIDER: PRJNA940427 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Similar Datasets

Circular RNA hsa_circ_0064559 is identified to affect the progression of colorectal cancer

Project description:Circular RNA hsa_circ_0064559 is identified to affect the progression of colorectal cancer

| PRJNA862888 | ENA

Circular RNA hsa_circ_0064559 is identified to affect the progression of colorectal cancer [PrimeView]

Project description:A series of circular RNAs (circRNAs) play a pivotal role in the pathogenesis of CRC.We found that hsa_circ_0064559 knockdown had the most significant reduction in the proliferation of CRC cells. The expressed genes(DEGs) between shEV group (n=3) and shCIRC group (n=3) from RKO cells were analyzed on Affymetrix GeneChip primeview human gene expression array (Affymetrix, CA, USA).

2023-06-14 | GSE226489 | GEO

Circular RNA hsa_circ_0064559 is identified to affect the progression of colorectal cancer

Project description:In the present study, six pairs of matched CRC and normal colorectal tissue samples were searched for genes that may influence proliferation. Affymetrix Clariom D array research revealed 13 genes that may be engaged in the progression of CRC.

2022-07-29 | GSE209892 | GEO

Hsa_circ_101555 functions as a competing endogenous RNA of miR-597-5p to promote colorectal cancer progression [Circular RNAs]

Project description:Circular RNAs (circRNAs) represent critical roles in the biology of various cancers. However, their expression patterns and biological functions in human colorectal cancer (CRC) remain largely unknown. The aim of this study was to explore circRNAs profiles in CRC and investigate key circRNAs involved in CRC tumourigenesis and progression.

2019-02-06 | GSE126094 | GEO

Circular RNAs expression profiling in human colorectal cancer

Project description:Circular RNAs expression profiling in human colorectal cancer

| PRJNA615670 | ENA

Identification of circular RNA and miRNAs during colorectal cancer progression and metastasis

Project description:Identification of circular RNA and miRNAs during colorectal cancer progression and metastasis

| PRJNA684603 | ENA

Regulation network of colorectal cancer specific enhancers in progression of colorectal cancer

Project description:Enhancers regulate multiple genes through higher-order chromatin structure and further affect cancer progression. Epigenetic changes in cancer cells activate several cancer specific enhancers that are silenced in normal cells. These cancer specific enhancers are potential therapeutic targets of cancer. However, functions and regulation network of colorectal cancer specific enhancers are still unknown. Here in this study, we profile colorectal cancer specific enhancers and reveal the regulation network of these enhancers by analysis of HiChIP, Hi-C and RNA-seq data. We propose the regulation network of colorectal cancer specific enhancers plays important role in progression of colorectal cancer.

2021-05-03 | GSE173699 | GEO

Key circular RNAs identified in male osteoporosis patients by whole transcriptome sequencing

Project description:Key circular RNAs identified in male osteoporosis patients by whole transcriptome sequencing

| PRJNA667727 | ENA

Extrachromosomal circular SUZ12 amplicon dictates retinoblastoma progression through reprogramming H3K27 methylation [eccDNA-seq]

Project description:Extrachromosomal circular DNA (eccDNA) is double-stranded circular DNA that is derived from but independent of chromosomal DNA. Owing to its nonchromosomal inheritance, eccDNA facilitates the amplification of oncogenes and expedites the process of genome evolution in tumor. However, the role of eccDNA in RB remains enigmatic. We combined Circle-Seq and RNA-Seq to identified crucial extrachromosomal circular oncogene amplicons. Herein, we revealed that extrachromosomal circular SUZ12 amplicon regulates H3K27me3 modification during the oncogenic progression of retinoblastoma. Conclusively, our study initially delineated an integrated picture of the eccDNA landscape in retinoblastoma and unveiled a novel SUZ12-containing eccDNA/H3K27me3 oncogenic mechanism where eccDNA dictates retinoblastoma progression through regulating transcription levels of linear DNA.

2023-07-02 | GSE235888 | GEO

Roles of circular RNA in cardiac fibrosis

Project description:Heart failure is one of the leading causes of death and it often accompanies activation of quiescent cardiac myofibroblasts, which results in cardiac fibrosis and resulting cardiac remodeling. Circular RNA, one form of non-coding RNA discovered recently, is formed by backsplicing of 3’ end to 5’ end of exons and is known to be closely related to the variety of pathophysiological function as well as normal homeostasis. However, its roles in the cardiovascular diseases, especially in cardiac fibrosis, are not fully studied. Circular RNAs (circRNAs) are formed by backsplicing events of 3′ end to 5′ end. To identify circRNA candidates, RNA sequencing (RNA-seq) datasets were obtained from transverse aortic constriction (TAC)-induced hearts. Especially, we were interested in cardiac fibroblast-specific circRNAs that affect its differentiation and cardiac fibrosis. Thus, in the present study, by utilizing RNA sequencing analysis followed by diverse bioinformatic or biochemical studies, we identified and characterized circRNA that may affect the pathologic remodeling of heart.

2023-12-14 | GSE240332 | GEO

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data