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Transcriptomic profiling in NUAK1 KO neurons

ABSTRACT: Transcriptomic profiling in NUAK1 KO neurons

PROVIDER: PRJNA944126 | ENA |

REPOSITORIES: ENA

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			Action	DRS
	SRR23828838.fastq.gz	Fastqsanger.gz
	SRR23828839.fastq.gz	Fastqsanger.gz
	SRR23828840.fastq.gz	Fastqsanger.gz
	SRR23828841.fastq.gz	Fastqsanger.gz
	SRR23828842.fastq.gz	Fastqsanger.gz

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Transcriptomic profiling in NUAK1 KO neurons

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Roles of the kinase NUAK1 on spliceosome in the mouse cortex

Project description:The project focuses on the protein kinase NUAK1, which controls the development of brain cortical connectivity in mice. Recent data suggest that NUAK1 is involved in the regulation of the spliceosome and more broadly of mRNA biology. The aim of this project is to test whether inactivation of NUAK1 (constitutive KO) affects the expression level of genes relevant for cortical development in the embryonic brain. We collected the cortex of embryos (littermates) at the late embryonic developmental stage (E18.5, i.e. just before birth). The samples will be either KO or WT (controls). We collected the samples on the same day, under the same conditions, and as far as possible we made homogeneous groups: same litter, same proportion of males/females.

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Comparison of the transcriptomic impact of NRF2 depletion with that of NUAK1 depletion in SW480 colorectal cancer cells

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