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Single-cell RNAseq analysis of wild type and Socs3 cKO retinal immune cells

ABSTRACT: Single-cell RNAseq analysis of wild type and Socs3 cKO retinal immune cells

PROVIDER: PRJNA947200 | ENA |

REPOSITORIES: ENA

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Single-cell RNAseq analysis of wild type and Socs3 cKO retinal immune cells

Project description:Myeloid SOCS3 deficiency leads to increased retinal neovascularization in an oxygen-induced retinopathy mouse model. To investigate the role of SOCS3 in the function of myeloid lineage cells, particular microglia during retinopathy, total immune cells were sorted from wildtype and myeloid Socs3 knockout mice with retinopathy applied for single-cell RNAseq analysis by 10X Genomics technology.

2024-02-25 | GSE227861 | GEO

RNAseq analysis of the global retinal transcriptome of rod photoreceptor-specific Dicer1 conditional knockout mice and control littermates

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Insights into gene expression profiles induced by Socs3 depletion in Keratinocytes

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