Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

CWC15 is required for miRNA accumulation

ABSTRACT: CWC15 is required for miRNA accumulation

PROVIDER: PRJNA950078 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR24008167.fastq.gz	Fastqsanger.gz
	SRR24008168.fastq.gz	Fastqsanger.gz
	SRR24008169.fastq.gz	Fastqsanger.gz
	SRR24008170.fastq.gz	Fastqsanger.gz

Items per page:

1 - 4 of 4

Similar Datasets

CWC15 is required for miRNA accumulation

Project description:To test if CWC15 is required for miRNA accumulation, an artificial miRNA (amiRCWC15) targeting 5’ UTR (Untranslated region) was used to knockdown the transcript levels of CWC15. Next, to test the effect of CWC15 on miRNA accumulation at global levels, flower inflorescences of four-week old col-0 and amiRCWC15 were collected, and total RNA was extracted by Trizol for Illumina deep sequencing analyses of miRNA profile.

2023-05-01 | GSE228510 | GEO

Dynamic regulation of miRNA accumulation during C. elegans larval development [miRNA-Seq]

Project description:Dynamic regulation of miRNA accumulation during C. elegans larval development [miRNA-Seq]

| PRJNA1069738 | ENA

NTP4 modulates miRNA accumulation via asymmetric modification of miRNA-3p/5p duplex

Project description:NTP4 modulates miRNA accumulation via asymmetric modification of miRNA-3p/5p duplex

| PRJNA634468 | ENA

Dynamic regulation of miRNA accumulation during C. elegans larval development

Project description:Dynamic regulation of miRNA accumulation during C. elegans larval development

| PRJNA1030343 | ENA

Endocardial HDAC3 is required for myocardial trabeculation [miRNA-seq]

Project description:Endocardial HDAC3 is required for myocardial trabeculation [miRNA-seq]

| PRJNA955259 | ENA

XPO5 is required for miRNA biogenesis and promotes primary miRNA processing independent of RanGTP

Project description:XPO5 is required for miRNA biogenesis and promotes primary miRNA processing independent of RanGTP

| PRJNA438688 | ENA

The effect of SEAP1 on the accumulation of miRNAs and mRNAs

Project description:SE-Associated Protein 1 (SEAP1), is a conserved protein in eukaryotes. Its orthologs, SART3 and PRP24 from metazoans and yeast play essential roles in splicing. Here, we report that SE-Associated Protein 1 (SEAP1), is required for miRNA biogenesis in Aradopsis. Lack of SEAP1 causes embryo lethality and knockdown of SEAP1 by an artificial miRNA (amiRSEAP1) causes pleiotropic growth defects and reduction in miRNA accumulation, accompanied with increased levels of target transcripts. SEAP1 associates with the RNase III enzyme Dicer-like 1(DCL1) complex, which processes primary miRNA transcripts (pri-miRNAs) into miRNAs, and seems to promote the interaction of the DCL1 complexes with pri-miRNAs. SEAP1 is also required for pri-miRNA accumulation. However, it does not affect the transcription of pri-miRNAs, suggesting it may indirectly or directly stabilize pri-miRNAs. SEAP1 also affects the spicing of pri-mRNAs. These results suggest that SEPA1 promotes miRNA biogenesis by positively modulating pri-miRNA splicing, processing and stability. We also find that intron retention in amiRSEAP1 is altered at global levels, linking SEAP1 to spicing. Collectively, our results uncover the function of SEAP1 in plants.

2021-04-12 | GSE171865 | GEO

miRNA analyses of genetic factors and the role of carotenoid accumulation in adductor muscles of QN Orange scallops

Project description:QN Orange scallop was interspecific hybrids with orange adductor muscles. Previous studies shown the accumulation of carotenoids was present in QN Orange scallops. In this study, analysis of miRNA expression profiles was performed to explore possibly regulatory patterns in carotenoid accumulation in adductor muscles of QN Orange scallops. Based on small RNA sequencing, a total of 3289 miRNAs and 91 differential expression miRNAs were identified between white and orange adductor muscles, respectively. GO and KEGG enrichment analysis of target genes of DE miRNA enriched in the transmembrane transporter activity-related pathways, kinase activity-related pathways, signal transduction-related pathways, ABC transporters, Retinol metabolism, lipid related metabolism and calcium signaling pathway.

2024-11-10 | GSE248569 | GEO

Translation is required for miRNA-dependent decay of endogenous transcripts.

Project description:Translation is required for miRNA-dependent decay of endogenous transcripts.

| PRJNA599577 | ENA

miRNAs are required for post-induction stage sweat gland development [miRNA]

Project description:miRNAs modulate processes in development, aging and cancer formation. However, miRNA function in sweat gland development has not been previously studied. By generating skin specific Dicer knockout mice, we show that miRNAs are required for post-induction stage sweat gland development.

2016-12-13 | GSE86295 | GEO

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data