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Tumor-infiltrating gamma delta T-cells reveal exhausted subsets with remarkable heterogeneity in colorectal cancer

ABSTRACT: Tumor-infiltrating gamma delta T-cells reveal exhausted subsets with remarkable heterogeneity in colorectal cancer

PROVIDER: PRJNA953157 | ENA |

REPOSITORIES: ENA

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			Action	DRS
	SRR24101261_1.fastq.gz	Fastqsanger.gz
	SRR24101261_2.fastq.gz	Fastqsanger.gz
	SRR24101262_1.fastq.gz	Fastqsanger.gz
	SRR24101262_2.fastq.gz	Fastqsanger.gz

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Tumor-infiltrating gamma delta T-cells reveal exhausted subsets with remarkable heterogeneity in colorectal cancer

Project description:Here, we sought to investigate the expression pattern of inhibitory receptors and functional state of TI-γδ T-cells, and reveal the features of exhausted TI γδ T-cells in the TME of CRC. In this study, the γδ T-cell subpopulations and gene expression profiles of TI-γδ T-cells and colonic intraepithelial lymphocytes (IELs) were analyzed by single-cell RNA sequencing (scRNA-seq).

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