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Role of SRSF5 in HeLa cells

ABSTRACT: Role of SRSF5 in HeLa cells

PROVIDER: PRJNA954011 | ENA |

REPOSITORIES: ENA

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			Action	DRS
	SRR24120240.fastq.gz	Fastqsanger.gz
	SRR24120241.fastq.gz	Fastqsanger.gz
	SRR24120242.fastq.gz	Fastqsanger.gz
	SRR24120243.fastq.gz	Fastqsanger.gz
	SRR24120244.fastq.gz	Fastqsanger.gz

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SRSF5 enhances the splicing of M gene by directly binding to M mRNA.

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Role of SRSF5 in HeLa cells

Project description:This SuperSeries is composed of the SubSeries listed below.

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Project description:To seach for factors with altered gene expression under the suppression of SRSF5 expression

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Project description:Nuclear entry of transcription factor HIPPI is mediated by its interacting partner Huntingtin Interacting Protein 1 (HIP1), a nuclear localization signal containing nucleo-cytoplasmic shuttling protein. In oredr to investigate the role of HIP1 in HIPPI mediated transcriptional regulation in cell, here we performed microarray experiments using stable HIP1 knocked down HeLa cells (Hip1Si) exogenously expressing Green fluorescent protein tagged HIPPI. Total RNA extracted from HIP1 knocked down HeLa cells (Hip1Si) transfected with empty GFP vector served as control and Total RNA extracted from Hip1Si cells transfected with GFP-Hippi construct served as test. Biological replicates: 4

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