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Milk fat miRNome changes in response to LPS challenge in Holstein cows

ABSTRACT: Milk fat miRNome changes in response to LPS challenge in Holstein cows

PROVIDER: PRJNA954727 | ENA |

REPOSITORIES: ENA

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Milk fat miRNome changes in response to LPS challenge in Holstein cows

Project description:Cows were fed a lactation diet at ad libitum intake (n = 6). At 27±3 days in milk, cows were injected with 50 µg of LPS E. coli in one healthy rear mammary quarter. Milk samples were collected just before LPS challenge (LPS-) and 6.5 h after LPS challenge (LPS+) from the same cows. Microarray analysis was performed using customized 8x60K ruminant miRNA microarrays to compare LPS- to LPS+ miRNome. MiRNome comparison between LPS- and LPS+ identified 37 differentially abundant miRNAs (q-value ≤ 0.05)

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