Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Burkitt lymphoma cells (Ramos cell line), wild type and SP140 knockout

ABSTRACT: Burkitt lymphoma cells (Ramos cell line), wild type and SP140 knockout

PROVIDER: PRJNA956073 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
		Other
	SRR20167195_1.fastq.gz	Fastqsanger.gz
	SRR20167195_2.fastq.gz	Fastqsanger.gz
	SRR20167196_1.fastq.gz	Fastqsanger.gz
	SRR20167196_2.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 28

Similar Datasets

H3K27me3 ChIP-seq in Burkitt lymphoma cells (Ramos cell line), wild type and SP140 knockout

Project description:Sp140 is a lymphocytic-restricted protein, an epigenetic reader working as a corepressor of genes implicated in inflammation and orchestrating macrophage transcriptional programs to maintain cellular identity. Reduced Sp140 expression is associated both to autoimmune diseases and blood cancer. However, the molecular mechanisms that link Sp140 altered protein levels to detrimental effects on the immune response and cellular growth, as well as the interactors through which Sp140 promotes gene silencing, remain elusive. In this work, we have applied a multi-omics approach (i.e. interactomics, ChIP-seq and proteomics) in two Burkitt lymphoma cell lines to identify both interactors and target genes of endogenous Sp140. We found that Sp140 interacts with the PRC2 and NuRD complexes and we demonstrated that Sp140 interaction with PRC2 is functional and directs H3K27me3 deposition on a set of target genes related to cellular growth and leukaemia progression.

2024-11-21 | GSE218453 | GEO

SP140 ChIP-seq for Daudi and Ramos cell lines

Project description:Study of the effect of SP140 deletion on the distribution of H3K27me3 in two independent Burkitt''s Lymphoma cell lines (DAUDI and Ramos).

2024-11-21 | GSE229801 | GEO

Sp140 interactome analysis and proteomic analyis of WT vs Sp140 KO in Burkitt lynphoma

Project description:Interactomic anaysis of Sp140 in Burkitt lynphoma and proteomic analyis of WT vs Sp140 KO in Ramos cell line

2024-11-21 | PXD036287 | Pride

H3K27me3 ChIP-seq in Burkitt lymphoma cells (Ramos cell line), wild type and SP140 knockout

Project description:H3K27me3 ChIP-seq in Burkitt lymphoma cells (Ramos cell line), wild type and SP140 knockout

| PRJNA903881 | ENA

ChIP-seq analysis done for MBD3 before and after SP140 knockout in Ramos cells

2024-11-21 | GSE208134 | GEO

Burkitt lymphoma cells (Ramos cell line), wild type and SP140 knockout

Project description:This SuperSeries is composed of the SubSeries listed below.

2024-11-21 | GSE229802 | GEO

Burkitt lymphoma cells vs. Lymphoblastoid B cells

Project description:To identify genes mediating tumor transformation we compared the transcriptome of five Burkitt lymphoma (BL) cell lines (tumor cells) with that of a pool of three lymphoblastoid B-cell lines (LCL; immortal, but not tumor cells). Each BL cell line was considered as a biological replicate. BL cell lines: DG-75, Ramos, BL2, Mutu-I and Akata. LCL cell lines: X50-7, IB4 and Dana.

2015-09-30 | GSE41865 | GEO

Expression data from Burkitt lymphoma cases

Project description:Burkitt lymphoma is the commonest cancer in children in Africa. We compared the gene expression profiles of African Burkitt lymphoma patients with those of cases presented in Western countries in both immunocompetent (sporadic Burkitt lymphoma) and HIV-infected patients (immunodeficiency associated Burkitt lymphoma). We used microarrays to detail the global programme of gene expression in different subtypes of Burkitt lymphoma.

2011-01-20 | GSE26673 | GEO

Transcription profiling of Burkitt lymphoma cases

2011-01-20 | E-GEOD-26673 | biostudies-arrayexpress

SP140 ChIP-seq for Daudi and Ramos cell lines

Project description:SP140 ChIP-seq for Daudi and Ramos cell lines

| PRJNA956075 | ENA