Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Methylation data from human retina samples profiled with Infinium HumanMethylationEPIC BeadChip

ABSTRACT: Methylation data from human retina samples profiled with Infinium HumanMethylationEPIC BeadChip

PROVIDER: PRJNA966249 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Similar Datasets

Methylation data from nine tissues from GTEx samples profiled with Infinium HumanMethylationEPIC BeadChip

Project description:Genome wide DNA methylation profiling of tissue samples from GTEx donors. The Infinium HumanMethylationEPIC BeadChip was used to obtain DNA methylation profiles across approximately 850,000 CpGs sites from 1000 tissue samples.

2022-09-16 | GSE213478 | GEO

Methylation data from nine tissues from GTEx samples profiled with Infinium HumanMethylationEPIC BeadChip

Project description:Methylation data from nine tissues from GTEx samples profiled with Infinium HumanMethylationEPIC BeadChip

| PRJNA880915 | ENA

Methylation data from human retina samples profiled with Infinium HumanMethylationEPIC BeadChip

Project description:Age-related macular degeneration (AMD) is a complex multifactorial disease with at least 34 loci contributing to genetic susceptibility. To gain functional understanding of AMD genetics, we generated DNA methylation profiles of retina from 160 individuals including both controls and cases at distinct stages of AMD. With genotypes over 8 million common single nucleotide polymorphisms (SNPs) in cis, we identified 37,453 methylation quantitative trait loci (mQTL) and by integrating transcriptome of the same samples we identified 12,505 eQTLs and 13,747 DNAm sites that affect gene expression (eQTMs). We then integrated the AMD-genome-wide association studies (GWAS) data with mQTLs and eQTLs ascertained 87 target genes that may contribute to AMD risk. Our studies expand the methylation landscape of retina and AMD leading to direct targets for biological evaluation.

2023-09-11 | GSE231536 | GEO

Evaluating The Infinium Human MethylationEPIC v2 BeadChip

Project description:Evaluating The Infinium Human MethylationEPIC v2 BeadChip

| PRJNA951687 | ENA

Characterisation and reproducibility of the HumanMethylationEPIC v2.0 BeadChip for DNA methylation profiling [WGBS]

Project description:Genome wide DNA methylation profiling of a suite of biological samples for technical evaluation of the HumanMethylationEPIC v2.0 BeadChip. Samples include prostate (LNCaP, PrEC) and breast cancer (MCF7, TAMR) cell lines, as well as primary tumour samples from prostate (SYN*) and breast (FD*).

2024-03-07 | GSE240481 | GEO

Characterisation and reproducibility of the HumanMethylationEPIC v2.0 BeadChip for DNAmethylation profiling [EPIC v1]

2024-03-07 | GSE240412 | GEO

Methylation data from stored peripheral blood leukocytes from African American participants in the GENOA study with Infinium HumanMethylationEPIC BeadChip

Project description:Methylation data from stored peripheral blood leukocytes from African American participants in the GENOA study with Infinium HumanMethylationEPIC BeadChip

| PRJNA864863 | ENA

Patient-derived primary cultures of paediatric high grade glioma and DIPG - molecular profiling by methylation array (Infinium HumanMethylationEPIC)

Project description:Molecular profiling by methylation array (Illumina Infinium HumanMethylationEPIC) in a panel of models generated under 2D (laminin matrix) and/or 3D (neurospheres) conditions fully credentialed by phenotypic and molecular comparison to the original tumour sample. Patient-derived in vitro primary cell cultures represent potentially useful tools for mechanistic and preclinical investigation based upon their retention of key features of tumour subgroups under experimental conditions amenable to high-throughput approaches.

2020-08-31 | E-MTAB-9297 | biostudies-arrayexpress

Genotyping analysis employing Illumina Infinium ImmunoArray-24 v2.0 BeadChip

Project description:Genotyping analysis employing Illumina Infinium ImmunoArray-24 v2.0 BeadChip

| PRJNA414780 | ENA

Characterisation and reproducibility of the HumanMethylationEPIC v2.0 BeadChip for DNAmethylation profiling

Project description:Characterisation and reproducibility of the HumanMethylationEPIC v2.0 BeadChip for DNAmethylation profiling

| PRJNA1003871 | ENA