Project description:Cardiopulmonary progenitors (CPPs) derived from mouse embryos have multi-directional differentiation potential. Their exosomes are not be investigated yet.
Project description:To investigate the function of exosomes from cardiopulmonary progenitors in the regulation of gene expression in endothelial cells.We performed gene expression profiling analysis using data obtained from RNA-seq of H9C2 treated with or without CPPs exosomes.
Project description:To investigate the function of exosomes from cardiopulmonary progenitors in the regulation of gene expressions in endothelial cells.We performed gene expression profiling analysis using data obtained from RNA-seq of HMEC-1 treated with or without CPPs exosomes.
Project description:The study aims to show that Sox9+ Chd1+ mouse embryonic lung progenitors can be isolated and expanded long-term in 3D culture while maintaining their multipotency. in vitro cultured Sox9+ Chd1+ lung progenitors transcriptionally resemble their in vivo counterparts and show significant difference from adult lung epithelial (Cdh1+ and EpCAM+) and non-epithelial (Cdh1- and EpCAM-) cells
Project description:The study aims to show that Sox9+ Chd1+ mouse embryonic lung progenitors can be isolated and expanded long-term in 3D culture while maintaining their multipotency. in vitro cultured Sox9+ Chd1+ lung progenitors transcriptionally resemble their in vivo counterparts and show significant difference from adult lung epithelial (Cdh1+ and EpCAM+) and non-epithelial (Cdh1- and EpCAM-) cells
Project description:Cardiopulmonary progenitors (CPPs) are a population of cells that still in study. We used single cell RNA sequencing (scRNA-seq) to analyze the diversity of cells isolated from in the mouse embryo heart, and CPPs we cultured in vitro.