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Epigenomic profiling of mouse nucleus accumbens at single-cell resolution

ABSTRACT: Epigenomic profiling of mouse nucleus accumbens at single-cell resolution

PROVIDER: PRJNA973943 | ENA |

REPOSITORIES: ENA

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Epigenomic profiling of mouse nucleus accumbens at single-cell resolution

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Project description:This dataset contains single-nucleus RNA sequencing results from adult rat brain (nucleus accumbens) and serves as the basis for characterization of transcriptional response to repeated cocaine injections (20mg/kg, intraperitoneal injection). The goal of this experiment was to define the transcriptional response to repeated cocaine across distinct cell types in the nucleus accumbens. Single-cell sequencing was carried out with FACS-sorted nuclei isolated from these experiments using the 10X Genomics Chromium single cell sequencing platform.

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Rat DNA methylation in the Nucleus Accumbens in Incubation of Cocaine Craving and treatments with DNA methylation modifying drugs

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