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Rosiglitazone and Trametinib to treat basal bladder tumors [ATAC-Seq]

ABSTRACT: Rosiglitazone and Trametinib to treat basal bladder tumors [ATAC-Seq]

PROVIDER: PRJNA980830 | ENA |

REPOSITORIES: ENA

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			Action	DRS
	SRR24843854_1.fastq.gz	Fastqsanger.gz
	SRR24843854_2.fastq.gz	Fastqsanger.gz
	SRR24843855_1.fastq.gz	Fastqsanger.gz
	SRR24843855_2.fastq.gz	Fastqsanger.gz
	SRR24843856_1.fastq.gz	Fastqsanger.gz

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Rosiglitazone and Trametinib to treat basal bladder tumors

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Trancriptional profiling of rat bladder after daily administration of Pioglitazone and Rosiglitazone in vivo (miRNA)

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Project description:Rosiglitazone, a peroxisome proliferator-activated receptor g (PPARg) agonist of the thiazolidinedione class, is a major insulin-sensitizing drug widely used to treat type-2 diabetes. Rosiglitazone causes myocardial hypertrophy in rodents and increases the risk of cardiac events in man. To better characterize its cardiac effects, male Wistar rats were orally administered 0, 10 or 80 mg/kg/day rosiglitazone.

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