Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Aliciella subsection Subnuda

ABSTRACT: Resolving relationships despite past hybridization in Aliciella subsection Subnuda (Polemoniaceae)

PROVIDER: PRJNA983746 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR25022900.fastq.gz	Fastqsanger.gz
	SRR25023000.fastq.gz	Fastqsanger.gz
	SRR25022901.fastq.gz	Fastqsanger.gz
	SRR25023001.fastq.gz	Fastqsanger.gz
	SRR25022902.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 174

Similar Datasets

Integrated Single-Cell Analysis in Chronic Lymphocytic Leukemia

Project description:<p>Intratumoral genetic heterogeneity has been characterized across cancers by genome sequencing of bulk tumors, including chronic lymphocytic leukemia (CLL). In order to more accurately identify subclones, define phylogenetic relationships, and probe genotype-phenotype relationships, we developed methods for targeted mutation detection in DNA and RNA isolated from thousands of single cells from five CLL samples. By clearly resolving phylogenic relationships, we uncovered mutated LCP1 and WNK1 as novel CLL drivers, supported by functional evidence demonstrating their impact on CLL pathways. Integrative analysis of somatic mutations with transcriptional states prompts the idea that convergent evolution generates phenotypically similar cells in distinct genetic branches, thus creating a cohesive expression profile in each CLL sample despite the presence of genetic heterogeneity. Our study highlights the potential for single-cell RNA-based targeted analysis to sensitively determine transcriptional and mutational profiles of individual cancer cells leading to increased understanding of driving events in malignancy.</p> <p>Reprinted from Genome Research, with permission from Publisher.</p>

| phs001372 | dbGaP

Project description:Phenotypic and life-history diversification in Amazonian frogs despite past introgressions

| PRJNA487055 | ENA

Revealing the genetic basis of natural bacterial phenotypic divergence

Project description:Application of a genome-wide linkage method to identify genotype-phenotype relationships between distantly related strains of E. coli. Each hybridization compares transposon footprinting results from a linkage library under a selective condition with those under a nonselective condition.

2013-11-30 | GSE45421 | GEO

Project description:Stable species boundaries despite ten million years of hybridization in tropical eels

| PRJNA590038 | ENA

Project description:Natural selection maintains species despite frequent hybridization in the desert shrub Encelia

| PRJNA675657 | ENA

Project description:Resolving the evolutionary relationships of molluscs with phylogenomic tools. Transcriptome or Gene expression

| PRJNA72139 | ENA

CGH analysis of Campylobacter jejuni isolates previously analyzed by Multi-Locus Sequence Typing

Project description:In this experiment, we hava analyzed a set of 45 C. jejuni strains by CGH and MLST in order to investigate whether the strain relationships inferred from the analysis of a small number of loci (MLST) reflect whole-genome gene conservation patterns observed by CGH. Keywords: individual hybridizations, comparative genomic hybridization

2008-04-21 | GSE9919 | GEO

Project description:A target enrichment probe set for resolving phylogenetic relationships in the coffee family, Rubiaceae

| PRJNA970862 | ENA

Project description:Resolving relationships in an exceedingly young Neotropical orchid lineage using Genotyping-by-sequencing data

| PRJNA579768 | ENA

Neutrophils facilitate the epicardial regenerative response after zebrafish heart injury

Project description:Despite extensive studies on endogenous heart regeneration within the past 20 years, the players involved in initiating early regeneration events are far from clear. Here, we assessed the function of neutrophils, the first-responder cells to tissue damage, during heart regeneration. We detected rapid neutrophil mobilization to the injury site after ventricular amputation, peaking at 1-day post-amputation (dpa) and resolving by 3 dpa. Further analyses indicated neutrophil mobilization coincides with peak epicardial cell proliferation and recruited neutrophils associated with activated, expanding epicardial cells at 1 dpa. Neutrophil depletion inhibited myocardial regeneration and significantly reduced epicardial cell expansion, proliferation, and activation. To explore the molecular mechanism of neutrophils on the epicardial regenerative response, we performed scRNA-seq analysis of 1 dpa neutrophils and identified enrichment of the FGF and ERK signaling pathways. Pharmacological inhibition of FGF signaling indicated its’ requirement for epicardial cell expansion, while neutrophil depletion blocked ERK signaling activation in epicardial cells. Altogether, our studies revealed that neutrophils quickly induce epicardial cells, which later accumulate at the injury site and contribute to heart regeneration.

2024-07-09 | GSE237761 | GEO

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data