Project description:ABRAXAS2 gene editing by CRISPR-Cas9 nuclease in heterozygous HFF for UROS inactivation. Fluorescent positive cell sorting for UROS and large rearrangements confirmation in chromosome 10q.
Project description:SORSC1 gene editing by CRISPR-Cas9 nuclease in heterozygous HFF for UROS inactivation. Fluorescent positive cell sorting for UROS and large rearrangements confirmation in chromosome 10q.
Project description:SORSC1 gene editing by CRISPR-Cas9 nuclease in heterozygous HFF for UROS inactivation. Fluorescent positive cell sorting for UROS and large rearrangements confirmation in chromosome 10q.
Project description:ABRAXAS2 or SORSC1 gene editing by CRISPR-Cas9 nuclease in heterozygous HFF KO P53 for UROS inactivation. Fluorescent positive cell sorting for UROS and large rearrangements confirmation in chromosome 10q.
Project description:ADRA2A or CPXM2 or TRUB1 or VCL or PLEKHA1 gene editing by CRISPR-Cas9 nuclease in heterozygous HFF for UROS inactivation. Fluorescent positive cell sorting for UROS and large rearrangements confirmation in chromosome 10q.
Project description:ABRAXAS2 gene editing by CRISPR-Cas9 nuclease or before editing in heterozygous HFF for UROS inactivation. Fluorescent positive cell sorting for UROS or without cell sorting and large rearrangements confirmation in chromosome 10q.