Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Oral spirochete Treponema denticola intraoral infection and periodontitis in C57BL/6J mice [8_weeks_Td_data]

ABSTRACT: Oral spirochete Treponema denticola intraoral infection and periodontitis in C57BL/6J mice [8_weeks_Td_data]

PROVIDER: PRJNA985760 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Similar Datasets

Oral spirochete Treponema denticola intraoral infection and periodontitis in C57BL/6J mice

Project description:Oral spirochete Treponema denticola intraoral infection and periodontitis in C57BL/6J mice

| PRJNA985757 | ENA

Oral spirochete Treponema denticola intraoral infection and periodontitis in C57BL/6J mice [8_weeks_sham_data]

Project description:Oral spirochete Treponema denticola intraoral infection and periodontitis in C57BL/6J mice [8_weeks_sham_data]

| PRJNA985758 | ENA

Oral spirochete Treponema denticola intraoral infection and periodontitis in C57BL/6J mice [16_weeks_Td_data]

Project description:Oral spirochete Treponema denticola intraoral infection and periodontitis in C57BL/6J mice [16_weeks_Td_data]

| PRJNA985762 | ENA

Oral spirochete Treponema denticola intraoral infection and periodontitis in C57BL/6J mice [16_weeks_sham_data]

Project description:Oral spirochete Treponema denticola intraoral infection and periodontitis in C57BL/6J mice [16_weeks_sham_data]

| PRJNA985759 | ENA

Oral spirochete Treponema denticola intraoral infection and periodontitis in C57BL/6J mice

Project description:Individual miRNA analyzed were successfully constructed through nanostring technology of a total of 577 mouse miRNAs in 20 number of SHAM mice and 20 number of T. denticola infected mice, which have been euthanized on the end of 16 weeks infection study.

2023-07-24 | GSE235373 | GEO

Oral spirochete Treponema denticola intraoral infection and periodontitis in C57BL/6J mice [16_weeks_Td_data]

2023-07-24 | GSE235372 | GEO

Oral spirochete Treponema denticola intraoral infection and periodontitis in C57BL/6J mice [16_weeks_sham_data]

2023-07-24 | GSE235371 | GEO

Oral spirochete Treponema denticola intraoral infection and periodontitis in C57BL/6J mice [8_weeks_Td_data]

2023-07-24 | GSE235370 | GEO

Oral spirochete Treponema denticola intraoral infection and periodontitis in C57BL/6J mice [8_weeks_sham_data]

2023-07-24 | GSE235369 | GEO

Treponema denticola transcriptional profiles in serum-restricted conditions

Project description:Treponema denticola is a major pathogen in periodontal disease, frequently isolated from lesions of chronic periodontitis. The ability to adopt its environment is believed to be important for T. denticola in colonizing and proliferating in the gingival crevice. T. denticola use serum as a major nutrient source in the gingival crevices, suggesting that this microorganism utilize serum components to proliferate in gingival crevice. The purpose of this study was to identify T. denticola serum utilization genes. Precultured T. denticola were suspended in tryptone-yeast extract-gelatin-volatile fatty acids medium containing 0, 1 and 10% serum, and incubated anaerobically for 17 h. Total RNA was isolated and T. denticola gene expression was compared by microarray and reverse transcription-polymerase chain reaction. In serum-depleted conditions, the expression of a potential hydroxylamine reductase, several ABC transporters, and phosphoenolpyruvate synthase were increased, while methyl-accepting chemotaxis proteins and a transcriptional regulator were decreased. The results suggest that T. denticola may uptake serum components via ABC transporters. Decreased dmcA expression with decreased serum concentration suggests its involvement in chemotaxis toward serum-rich environments.

2018-07-20 | GSE110856 | GEO

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data