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Escherichia coli strain:Ecoli1344_LBHALD | isolate:The strain was collected from urine from a male patient in the urology departement of Aristide le Dantec National University Teaching Hospital of Dakar Senegal

ABSTRACT: Escherichia coli strain:Ecoli1344_LBHALD | isolate:The strain was collected from urine from a male patient in the urology departement of Aristide le Dantec National University Teaching Hospital of Dakar Senegal Genome sequencing

PROVIDER: PRJNA987639 | ENA |

REPOSITORIES: ENA

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Klebsiella pneumoniae subsp. pneumoniae strain:Kp3739_LBHALD | isolate:The strain was collected from urine from a patient in the urology departement of Aristide le Dantec National University Teaching Hospital of Dakar Senegal

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Enterobacter hormaechei strain:Eh202_LBHALD | isolate:Sample obtained from a patient from Anaesthesia and Intensive Care unit in Aristide Le Dantec National University teaching hospital in Dakar Senegal

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Pre-hospital delay in patients with ischemic stroke in the Fann Teaching Hospital, Dakar, Senegal in 2020.

Project description:Introductionstroke is a cerebrovascular disease. Early reperfusion in neurovascular units can reduce its morbidity and mortality. Even when neurovascular units exist, patients usually arrive late in the emergency department. to the purpose of this study was to determine prehospital delay in patients with acute ischemic stroke and associated factors.Methodswe conducted a retrospective cross-sectional study in the neurology department of the Fann University Hospital in Dakar from January 1s t to June 30th, 2020. We included patients younger than 80 years seen in the emergency unit for ischemic stroke. The median time to presentation was calculated based on the time of stroke onset and that of arrival at the hospital. Multivariate analysis was used to determine factors associated with prehospital delay.Resultsa total of 56 patients were enrolled, among whom 58.6% arrived at the hospital in less than 3 hours. Of them, 37.5% presented to a level 3 or 4 hospital first. Less than 34% of our patient presented to a level 2-3 hospital in less than 3 hours. Based on bi- and multivariate analysis, being married (OR = 7.2 [CI à 95%: 1.5 - 35.8]), being a female (OR = 5.5 [CI à 95%: 1.5 - 19.8]) and having stroke during week days (OR = 4.3 [CI à 95%: 1.3-13.9]) were associated with prehospital delay.Conclusionmost of our patients arrived late at a level 2 or 3 hospital. Being a married woman increased the risk of late arrival. This study highlights the importance of improving awareness in order to increase the proportion of patients potentially eligible for revascularization.

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Hypertension and Obesity in Dakar, Senegal.

Project description:BackgroundCardiovascular disease is a major public health problem in many sub-Saharan African countries, but data on the main cardiovascular risk factors-hypertension and obesity-are almost nonexistent in Senegal. The aims of this study were therefore (i) to report the prevalence, awareness, treatment and control of hypertension among adults in Dakar, (ii) to assess the prevalence of general and central obesity, and (iii) to analyze the association between hypertension and general and central obesity.MethodsA cross-sectional survey was carried out in 2015 on a representative sample of 1000 dwellers of the Senegalese capital aged 20-90.ResultsThe overall prevalence of hypertension was 24.7%. Among hypertensive respondents, 28.4% were aware of their condition; 16.0% were on antihypertensive medication; 4.9% had controlled blood pressure. The frequency of doctor visits was a significant predictor of awareness (OR = 2.16; p<0.05) and treatment (OR = 2.57; p<0.05) of hypertension. The prevalence of underweight, overweight and general obesity were 12.6%, 19.2% and 9.7% respectively. The prevalence of central obesity was 26% by WC and 39.8% by WHtR. General obesity and central obesity by WHtR significantly predicted HTN among men and women, but not central obesity by WC.ConclusionsThis study has demonstrated a high prevalence of hypertension in Dakar and a high prevalence of obesity among women-particularly among older women. The awareness, treatment, and effective control of hypertension are unacceptably low. The blood pressure of women with general obesity, and men with central obesity, in the community should be monitored regularly to limit the burden of cardiovascular disease in Senegal.

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Project description:We repoted the Glioblastoma stem cells(GSCs) infected by two strains of ZIKA virus, the Brazil and Dakar strains. The ZIKV was added into the medium of GSCs for 48 hours, the RNA was harvested after ZIKV infection. We found that the GSCs up-regulated the Type 1&2 interferons after infected by ZIKV

2017-08-23 | GSE102924 | GEO

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