Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Identification of RNF213 as a potential suppressor of local invasion in intrahepatic cholangiocarcinoma

ABSTRACT: Identification of RNF213 as a potential suppressor of local invasion in intrahepatic cholangiocarcinoma

PROVIDER: PRJNA987989 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR25046513_1.fastq.gz	Fastqsanger.gz
	SRR25046513_2.fastq.gz	Fastqsanger.gz
	SRR25046514_1.fastq.gz	Fastqsanger.gz
	SRR25046514_2.fastq.gz	Fastqsanger.gz
	SRR25046515_1.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 36

Similar Datasets

Identification of RNF213 as a potential suppressor of local invasion in intrahepatic cholangiocarcinoma

Project description:Intrahepatic cholangiocarcinoma (ICC) is a lethal cancer arising from intrahepatic bile ducts in the liver. In the intraductal growth (IDG) type, also referred to as intraductal papillary neoplasm of the bile duct (IPNB), a rare subtype of ICC, cancer cells originating within the bile duct usually invade and infiltrate the nearby liver tissues, resulting in local invasion. IPNB can serve as a good disease model to study the mechanism of local invasion, which is the earliest step of metastasis. Here, we aimed to identify the genes associated with local invasion by comparing the somatic mutations of the matched IPNB tissues with and without local invasion from a set of 11 patients using the Ion AmpliSeq Comprehensive Cancer Panel. Somatic mutation profiling analysis identified RNF213 as a potential candidate gene associated with local invasion in ICC patients. We established stable RNF213-knockdown and shControl cholangiocarcinoma (CCA) cell lines (HuCCT1, YSCCC, and KKU-100). Next, the expression profiling of the RNF213-knockdown and shContol CCA cell lines was analyzed by RNA sequencing.

2024-07-24 | GSE235891 | GEO

Homo sapiens strain:Intrahepatic cholangiocarcinoma

Project description:Homo sapiens strain:Intrahepatic cholangiocarcinoma Exome

| PRJNA207681 | ENA

Gene expression profiles of bulk tumor tissues of intrahepatic cholangiocarcinoma

Project description:We report the gene expression profiles of bulk tumor tissues of intrahepatic cholangiocarcinoma

2020-12-30 | GSE162396 | GEO

Distinct immune escape mechanisms identified in intrahepatic cholangiocarcinoma by immune classification

Project description:A \"Cartes d'Identite des Tumeurs\" (CIT) project from the french Ligue Nationale Contre le Cancer (http://cit.ligue-cancer.net). This serie showed the heterogeneity of tumor microenvironment across intrahepatic cholangiocarcinoma.

2019-12-28 | E-MTAB-6389 | biostudies-arrayexpress

Integrative Transcriptomic Profiling reveals Hepatic Stem-like Phenotype and Interplay of EMT and miR-200c in Intrahepatic Cholangiocarcinoma

Project description:This SuperSeries is composed of the following subset Series: GSE32879: Integrative Transcriptomic Profiling reveals Hepatic Stem-like Phenotype and Interplay of EMT and miR-200c in Intrahepatic Cholangiocarcinoma [mRNA] GSE32957: Integrative Transcriptomic Profiling reveals Hepatic Stem-like Phenotype and Interplay of EMT and miR-200c in Intrahepatic Cholangiocarcinoma [miRNA] Refer to individual Series

2012-09-28 | E-GEOD-32958 | biostudies-arrayexpress

Homo sapiens

Project description:Identification of RNF213 as a potential suppressor of local invasion in intrahepatic cholangiocarcinoma

| PRJNA985418 | ENA

Gene expression signatures for Intrahepatic cholangiocarcinoma

Project description:Gene expression signatures for Intrahepatic cholangiocarcinoma

| PRJNA752353 | ENA

Applications of Next Generation Sequencing in intrahepatic cholangiocarcinoma

Project description:We generated 100 M of high-quality sequencing reads (~10 M per sample) and catalogued the expression profiles of 1643 microRNA in each sample. The analysis showed differences of microRNAs between intrahepatic cholangiocarcinoma and normal bile duct tissues.

2019-12-10 | GSE93366 | GEO

The proteome and phosphoproteome of Intrahepatic Cholangiocarcinoma patients

Project description:The proteome and phosphoproteome of Intrahepatic Cholangiocarcinoma patients

2022-09-23 | PXD037011 |

Gene expression profiling associated with knockdown of LKB1 in human intrahepatic cholangiocarcinoma

Project description:The experiment was designed to display differential gene expression profiling in three human intrahepatic cholangiocarcinoma (ICC) cells upon knockdow of LKB1 tumor suppressor, by using RNAseq technology.

2014-07-29 | GSE59855 | GEO

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data