Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Circular RNA sequencing of P0 and P2 generation chondrocytes

ABSTRACT: Circular RNA sequencing of P0 and P2 generation chondrocytes

PROVIDER: PRJNA992523 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR25195160_1.fastq.gz	Fastqsanger.gz
	SRR25195160_2.fastq.gz	Fastqsanger.gz
	SRR25195161_1.fastq.gz	Fastqsanger.gz
	SRR25195161_2.fastq.gz	Fastqsanger.gz
	SRR25195162_1.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 12

Similar Datasets

Circular RNA sequencing of P0 and P2 generation chondrocytes

Project description:Purpose: Circular RNA sequencing was used to find out differentially expressed CircRNAs between P0 generation samples and P2 generation samples. Method: chondrocyte CircRNAs profiles of P0 generation samples and P2 generation samples were analyzed.

2023-08-02 | GSE236856 | GEO

Mutation in H82 P0,P1,P2,P3,P4 tumors

Project description:Mutation in H82 P0,P1,P2,P3,P4 tumors

| PRJNA672788 | ENA

Circular RNA sequencing of chondrocytes treated with or without cholesterol

Project description:Circular RNA sequencing of chondrocytes treated with or without cholesterol

| PRJNA1006430 | ENA

Efficient generation of stable chondrocytes from human iPSC through early induction of a pre-chondrogenic population

Project description:Regeneration of human cartilage is inherently inefficient; an abundant autologous source like human induced pluripotent stem cells (hiPSC) is therefore attractive for engineering cartilage. Here, we report a defined growth factor based protocol for differentiating hiPSC into articular-like chondrocytes within two weeks with a high efficiency. The hiPSC-derived chondrocytes (hiChondrocytes) are stable and comparable to adult articular chondrocytes in global gene expression, extracellular matrix production and in their ability to generate cartilage tissue in vitro and in immune-deficient mice. Molecular characterization identified an early Sox9lowCD44lowCD140low pre-chondrogenic mesodermal population during hiPSC differentiation that eventually generates a homogenous population of Sox9highCD44highCD140high hiChondrocytes. Additionally, global gene expression analyses revealed two distinct Sox9-regulated gene networks in the Sox9low and Sox9high populations providing novel molecular insights into chondrogenic fate commitment and differentiation. Our findings present a favorable method for generation of hiPSC-derived articular chondrocytes in terms of safety and efficiency. 10 samples were analysed (duplicate sets of 5 time points) to assess changing gene expression over the course of differentiation from iPSC to hiChondrocyte. All samples were compared relative to the undifferentiated iPSC. Adult chondrocytes (2 samples) were also included for comparison. We analyzed the changes in gene expression with differentiation; genes with a fold-change â?¥ or â?¤1.5, with a difference in intensity of >100 and within the lower 90% confidence bound were selected.

2015-11-01 | E-GEOD-62914 | biostudies-arrayexpress

Runx1 Circular Chromosome Conformation Capture Sequencing in Mouse Hematopoietic Progenitor Cells

Project description:We have performed circular chromosome conformation capture sequencing (4C-seq) with six baits located at the Runx1 locus in the mouse hematopoietic progenitor cell line HPC-7. 4C baits were designed to the P1 and P2 promoters and to the previously characterised +24 hematopoietic enhancer (P1, P2 and 24), with secondary baits located at nearby cohesin/CTCF (cc) binding sites (P1cc, 24cc, P2cc).

2017-10-22 | GSE86994 | GEO

Paracoccus sp. P2 strain:P2

Project description:Paracoccus sp. P2 strain:P2 Genome sequencing

| PRJNA1150278 | ENA

Rhodopirellula sp. P2 strain:P2

Project description:Rhodopirellula sp. P2 strain:P2 Genome sequencing

| PRJNA932611 | ENA

RNA-seq of E11.5 TrkC neurons of Runx3-P2+/- and Runx3-P2-/- mice

Project description:To gain insight into the role of Runx3 in TrkC neurons we performed RNA-seq on E11.5 TrkC neurons isolated from cervical ganglia of Runx3-P2+/- and Runx3-P2-/- mice

2016-11-20 | GSE81140 | GEO

Project description:P2 Raw sequence reads

| PRJNA1090402 | ENA

Clostridioides difficile P2 strain:P2

Project description:Clostridioides difficile P2 strain:P2 Genome sequencing and assembly

| PRJNA85963 | ENA