Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Vibrio

ABSTRACT: Unveiling potential virulence determinants in Vibrio isolates from Anadara tuberculosa through whole genome analysis.

PROVIDER: PRJNA992554 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
		Other
	SRR31094202_1.fastq.gz	Fastqsanger.gz
	SRR31131500_1.fastq.gz	Fastqsanger.gz
	SRR31131501_1.fastq.gz	Fastqsanger.gz
	SRR31131502_1.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 17

Similar Datasets

undefined

Project description:Potential Virulence in Vibrio spp. from Anadara tuberculosa

| PRJEB64178 | ENA

Comparative proteomic profiling reveals specific adaptation of Vibrio anguillarum to oxidative stress, iron deprivation and humoral components of innate immunity

Project description:The gram-negative bacterium Vibrio (Listonella) anguillarum is the causative agent of vibriosis, a bacterial disease affecting aquacultural industry across the globe. The full mechanism of V. anguillarum pathogenesis is not completely understood, but many virulence determinants have been identified. The current study aimed to obtain molecular insights into the proteome response of the bacterium to several conditions mimicking vibriosis. Our data shed light on the adaptability of V. anguillarum to oxidative stress, iron limitations and the complement system, and offer potential virulence determinants associated in particular with septicemia over the course of vibriosis.

2021-11-25 | PXD025367 | Pride

Proteomics Analysis Reveals Previously Uncharacterized Virulence Factors in Vibrio proteolyticus

Project description:Members of the genus Vibrio include many pathogens of humans and marine animals that share genetic information via horizontal gene transfer. Hence, the Vibrio pan-genome carries the potential to establish new pathogenic strains by sharing virulence determinants, many of which have yet to be characterized. Here, we investigated the virulence properties of Vibrio proteolyticus, a Gram-negative marine bacterium previously identified as part of the Vibrio consortium isolated from diseased corals. We found that V. proteolyticus causes actin cytoskeleton rearrangements followed by cell lysis in HeLa cells in a contact independent manner. In search of the responsible virulence factor involved, we determined the V. proteolyticus secretome. This proteomics approach revealed various putative virulence factors, including active type VI secretion systems and effectors with virulence toxin domains; however, these type VI secretion systems were not responsible for the observed cytotoxic effects. Further examination of the V. proteolyticus secretome led us to hypothesize and subsequently demonstrate that a secreted hemolysin, belonging to a previously uncharacterized clan of the leukocidin superfamily, was the toxin responsible for the V. proteolyticus-mediated cytotoxicity in both HeLa cells and macrophages. Clearly, there remains an armory of yet-to-be discovered virulence factors in the Vibrio pan-genome that will undoubtedly provide a wealth of knowledge on how a pathogen can manipulate host cells.

2016-05-23 | MSV000079754 | MassIVE

California Vibrio cholerae CGH

Project description:Environmental isolates of Vibrio cholerae from California coastal water compared to reference strain N16961. A genotyping experiment design type classifies an individual or group of individuals on the basis of alleles, haplotypes, SNP's. Keywords: genotyping_design; array CGH

2007-07-17 | GSE8499 | GEO

Vibrio alginolyticus iTRAQ

Project description:In recent years, due to the influence of climate change and rising sea temperature, the incidence of Vibrio alginolyticus infections is increasing, and becoming the second most common Vibrio species reported in human illness. Therefore, better understanding of the pathogenic mechanism of V. alginolyticus infection is urgently needed. Vvrr1 (Vibrio virulence regulatory RNA 1) is a new found ncRNA predicted to be closely related to the adhesion ability of V. alginolyticus through the previous RNA-seq. In this study, the target genes of Vvrr1 were fully screened and verified by constructing Vvrr1 over-expressed strains and proteome sequencing technology.

2020-05-26 | PXD014375 | Pride

Anadara tuberculosa isolate:BMG1

Project description:Anadara tuberculosa isolate:BMG1 Genome sequencing

| PRJNA997345 | ENA

RNAseq analysis of Vibrio cholerae A1552 WT and ∆rvvA (∆VCA0257)

Project description:RNA-sequencing of Vibrio cholerae A1552 wild-type and ∆VCA0257 (∆rvvA) strains grown under virulence-inducing conditions (AKI).

2023-05-12 | GSE230781 | GEO

Proteomic analysis of Balneola and Vibrio isolates

Project description:Proteome profile of Balneola and Vibrio isolates established by next-generation proteomics

2022-05-20 | PXD031583 | Pride

Comparative genomic hybridization of Vibrio cholerae from California coastal water compared to reference strain N16961

Project description:Environmental isolates of Vibrio cholerae from California coastal water compared to reference strain N16961.

2007-05-23 | E-SMDB-4063 | biostudies-arrayexpress

Vibrio cholerae O395 toxSL33S vs toxSL33S delta rpoE

Project description:Transcriptional profiling of Vibrio Cholerae RpoE deletion mutant in toxSL33S mutation background Synchronized samples grown in virulence inducing conditions, strains independently grown and harvested

2015-08-26 | E-GEOD-72378 | biostudies-arrayexpress

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data