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Homo sapiens

ABSTRACT: Treatment of primary acute myelogenous leukemia (AML) specimens with parthenolide (PTL)

OTHER RELATED OMICS DATASETS IN: E-GEOD-7538

PROVIDER: PRJNA99367 | ENA |

REPOSITORIES: ENA

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E-GEOD-7538

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Project description:The effects of 7.5 micromolar parthenolide (PTL) were assessed on primary CD34+ acute myelogenous leukemia specimens obtained from 12 patients. Experiment Overall Design: Acute myelogenous leukemia (AML) specimens were obtained from 12 patients and CD34+ cells were isolated. For each patient, cells were cultured in vitro and exposed to either 7.5 micromolar parthenolide (PTL) or left untreated (UT) for 6 h. Total RNA was then harvested for global gene expression analysis.

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