Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Gene expression profile of human monocyte-derived macrophage stimulated with AGP, anti-CD74 antibody, CRP, and mycobacterium avium infaction.

ABSTRACT: Gene expression profile of human monocyte-derived macrophage stimulated with AGP, anti-CD74 antibody, CRP, and mycobacterium avium infaction.

PROVIDER: PRJNA994455 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR25257965.fastq.gz	Fastqsanger.gz
	SRR25257966.fastq.gz	Fastqsanger.gz
	SRR25257967.fastq.gz	Fastqsanger.gz
	SRR25257968.fastq.gz	Fastqsanger.gz
	SRR25257969.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 8

Similar Datasets

Gene expression profile of human monocyte-derived macrophage stimulated with AGP, anti-CD74 antibody, CRP, and mycobacterium avium infaction.

Project description:Macrophages are immune cells inctributing to several kinds of diseases, and activation status of macrophages are considered to be regulated by several stimulations. To test the gene expression change in activated macrophages, human monocyte-derived macrophages were stimulated with alpha1-acid glycoprotein (AGP), anti-CD74 blocking antobody, anti-CD74-agonistic antibody. Macrophages infected with Micobacterium avium were also tested. The mRNA expression in control, stimulated, infected macrophages were analysed.

2024-07-12 | GSE237240 | GEO

Gene expression profile of human monocyte-derived macrophage stimulated with AGP, anti-CD74 antibody, and mycobacterium avium infaction

2024-11-01 | GSE217996 | GEO

Gene expression profile of human monocyte-derived macrophage stimulated with AGP, anti-CD74 antibody, and mycobacterium avium infaction

Project description:Gene expression profile of human monocyte-derived macrophage stimulated with AGP, anti-CD74 antibody, and mycobacterium avium infaction

| PRJNA901873 | ENA

Gene expression profile of human monocyte-derived macrophage stimulated with anti-CD74 antibody(10mg/mL).

Project description:Gene expression profile of human monocyte-derived macrophage stimulated with anti-CD74 antibody(10mg/mL).

| PRJNA1057156 | ENA

CD74 downregulation in placental macrophages and its influence on trophoblast cells.

Project description:Preeclampsia is a disease of pregnant women, which is characterized by hypertension, proteinuria and chronic inflammation. There is a growing body of evidence that cause of preeclampsia lies within immunological aspect of pregnancy. This study aimed to analyze the role of CD74 in preeclampsia with a focus on its influence on communication between placental macrophages (Hofbauer cells) and trophoblasts. We have found CD74 to be highly dysregulated in preeclamptic placenta by real-time RT-PCR and Western blot methods. We identified Hofbauer cells to express the highest levels of CD74 in placenta by immunofluorescence and flow cytometry and that CD74 in preeclamptic Hofbauer cells is lower than in controls. We have performed a transcriptome analysis on human blood monocyte-derived macrophages that were non- or IL-4-activated and treated with small interfering RNA against CD74 (siRNA CD74) or non-targeting siRNA (siRNA non-targeting) as control.

2015-04-29 | E-MTAB-3309 | biostudies-arrayexpress

Mycobacterium avium subsp. paratuberculosis (MAP) during bovine monocyte-derived macrophage infection: untreated vs. bafilomcyin A1 treatment

Project description:Transcriptional profiling of M. avium subsp. paratuberculosis inside bovine monocyte-derived macrophages (MDMs; in vitro infection) during phagosome acidification at 30 min post-infection. M. avium subsp. paratuberculosis profiles from bafilomcyin A1 (acidification inhibitor) treated and untreated monocyte-derived macrophages were compared.

2016-07-29 | GSE84708 | GEO

Genome wide H3K4me2 detection after CD74 activation.

Project description:CD74 (invariant chain), expressed on B cells, is directly involved in shaping the B cell repertoire by regulating their survival in health and disease. Binding of its ligand, macrophage migration inhibitory factor (MIF), induces a cascade that results in CD74 intramembrane proteolysis, and the release of the CD74 intracellular domain (CD74-ICD). CD74-ICD translocates to the nucleus where it induces activation of transcription. In the current study, we characterized the transcription factor activity of CD74-ICD. Following histone modifications we are able to characterize CD74's binding sites as regulatory areas.

2022-11-03 | GSE181676 | GEO

CRP and FIS

Project description:CRP and FIS

| PRJNA412865 | ENA

Mycobacterium avium subsp. paratuberculosis (MAP) during bovine monocyte-derived macrophage infection: untreated vs. bafilomcyin A1 treatment

2016-07-29 | E-GEOD-84708 | biostudies-arrayexpress

Kluyvera sp. CRP

Project description:Kluyvera sp. CRP Genome sequencing

| PRJNA758164 | ENA