Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Listeria phage LP-125

ABSTRACT: Milk-evolved mutant Listeria Phage LP-125 raw sequence reads

PROVIDER: PRJNA997990 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR25405718_1.fastq.gz	Fastqsanger.gz
	SRR25405718_2.fastq.gz	Fastqsanger.gz
	SRR25405719_1.fastq.gz	Fastqsanger.gz
	SRR25405719_2.fastq.gz	Fastqsanger.gz
	SRR25405720_1.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 16

Similar Datasets

Listeria phage

Project description:Lab-evolved Mutant Listeria Phage Genomes and Sequencing Reads Genome sequencing and assembly

| PRJNA638358 | ENA

Listeria phage vB_LmoS_188

Project description:Listeria phage vB_LmoS_188 Genome sequencing

| PRJNA271556 | ENA

Listeria phage vB_LmoS_293

Project description:Listeria phage vB_LmoS_293 Genome sequencing

| PRJNA271557 | ENA

Listeria phage sp.

Project description:Listeria phage sp. Genome sequencing and assembly

| PRJNA896648 | ENA

Listeria phage HB17054

Project description:Listeria phage HB17054 Genome sequencing and assembly

| PRJNA835586 | ENA

Influence of the aminoglycoside antibiotic apramycin on host and phage DNA transcription during infection of S. venezuelae ATCC 10712 with phage Alderaan

Project description:Bacterial populations face the constant threat of viral predation exerted by bacteriophages (or phages). In response, bacteria have evolved a wide range of defense mechanisms against phage challenges. Here, we show that aminoglycosides, a well-known class of antibiotics produced by Streptomyces, are potent inhibitors of phage infection. We observed a broad phage inhibition by aminoglycosides. We demonstrate that aminoglycosides do not prevent the injection of phage DNA into bacterial cells but instead block an early step of the viral life cycle. In this context, we used RNA sequencing of S. venezuelae cells infected with phage Alderaan to comparatively investigate the influence of apramycin on phage DNA tanscription at two different time points after inital infection.

2021-04-30 | GSE171784 | GEO

Listeria phage SH3-3 isolate:Sweage

Project description:Listeria phage SH3-3 isolate:Sweage Genome sequencing

| PRJNA530861 | ENA

Homburgvirus LP-018 Has a Unique Ability to Infect Phage-Resistant Listeria monocytogenes.

Project description:Listeria phage LP-018 is the only phage from a diverse collection of 120 phages able to form plaques on a phage-resistant Listeria monocytogenes strain lacking rhamnose in its cell wall teichoic acids. The aim of this study was to characterize phage LP-018 and to identify what types of mutations can confer resistance to LP-018. Whole genome sequencing and transmission electron microscopy revealed LP-018 to be a member of the Homburgvirus genus. One-step-growth curve analysis of LP-018 revealed an eclipse period of ~60-90 min and a burst size of ~2 PFU per infected cell. Despite slow growth and small burst size, LP-018 can inhibit the growth of Listeria monocytogenes at a high multiplicity of infection. Ten distinct LP-018-resistant mutants were isolated from infected Listeria monocytogenes 10403S and characterized by whole genome sequencing. In each mutant, a single mutation was identified in either the LMRG_00278 or LMRG_01613 encoding genes. Interesting, LP-018 was able to bind to a representative phage-resistant mutant with a mutation in each gene, suggesting these mutations confer resistance through a mechanism independent of adsorption inhibition. Despite forming plaques on the rhamnose deficient 10403S mutant, LP-018 showed reduced binding efficiency, and we did not observe inhibition of the strain under the conditions tested. Two mutants of LP-018 were also isolated and characterized, one with a single SNP in a gene encoding a BppU domain protein that likely alters its host range. LP-018 is shown to be a unique Listeria phage that, with additional evaluation, may be useful in biocontrol applications that aim to reduce the emergence of phage resistance.

| S-EPMC6950383 | biostudies-literature

Transcriptomic profiling of LP lesions, hypertrophic LP (HLP) lesions, and healthy controls

Project description:The microarray experiment was employed to evaluate the gene expressions in skin lesions of LP, hypertrophic LP (HLP), and healthy controls.

2020-01-01 | GSE130403 | GEO

Staphylococcus phage

Project description:Staphylococcus evolved phage raw sequence reads

| PRJNA1008615 | ENA