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TranscriptomicsGene expression profile of a MDH2-mutated tumor
Transcriptional analysis of one primary paraganglioma One sample (primary paraganglioma) were hybridized onto a cDNA microarray in order to investigate differentially expressed genes
ORGANISM(S): Homo sapiens 
2015-04-08 | E-GEOD-56573 | biostudies-arrayexpress
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ProteomicsDeubiquitinase USP9X loss sensitizes renal cancer cells to mTOR inhibition
mTOR is a central regulator of mammalian metabolism and physiology. Aberrant hyperactivation of this pathway promotes tumor growth and metastasis and drives tumor resistance to chemotherapy and cancer drugs, making mTOR an attractive cancer therapeutic target. mTOR inhibitors have been approved to tr...
ORGANISM(S): Homo Sapiens (human) 
2023-06-14 | PXD040496 | Pride
Human Usp9x Ubiquitinase Renal cancer Mtor 
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ProteomicsHsa-miR-139-5p expression regulates the abundance of proteins related to poor survival cancer in CAL-62 thyroid cancer cell line
We studied the impact of hsa-miR-139-5p on the protein output by means of an iTRAQ-based approach. First, we established two CAL-62 isogenic cell lines expressing either the mature hsa-miR-139-5p or a non-targeting control upon a doxycycline inducible promoter (PTRE3G-tGFP, Dharmacon). Total proteins...
ORGANISM(S): Homo Sapiens (human) 
2019-08-13 | PXD011901 | Pride
Impact Thyroid cancer Hsa-mir-139-5p Cal-62 Itraq 
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TranscriptomicsGene expression profiling of pheochromocytoma (PCC)/paraganglioma (PGL) tumors
Transcriptional analysis of 84 primary pheochromocytoma (PCC)/paraganglioma tumors. 84 samples (primary pheochromocytoma (PCC)/paraganglioma tumors) were hybridized onto a cDNA microarray in order to investigate possible heterogeneity within these tumors
ORGANISM(S): Homo sapiens 
2010-12-31 | E-GEOD-19422 | biostudies-arrayexpress
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