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Proteomics,MultiomicsThe innate immune protein calprotectin promotes Pseudomonas aeruginosa and Staphylococcus aureus interaction
Microorganisms form biofilms containing differentiated cell populations. To determine factors driving differentiation, we study protein distributions in bacterial biofilms using shotgun proteomics. Notably, zinc- and manganese-depleted portions of the biofilm repress the production of anti-staphyloc...
ORGANISM(S): Pseudomonas Aeruginosa (strain Ucbpp-pa14) 
2016-06-22 | PXD004081 | Pride
Pa14 Biofilms Drip flow reactor Calprotectin Pseudomonas aeruginoa S100a9 S100a8 
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ProteomicsMouse kidney and cell lines LC-MS/MS
Zinc (Zn) is an essential micronutrient and cofactor for up to 10% of proteins in living organisms. During Zn limitation, specialized enzymes called metallochaperones are predicted to allocate Zn to specific metalloproteins. This function has been putatively assigned to G3E GTPase COG0523 proteins,...
ORGANISM(S): Mus Musculus (mouse) 
2023-07-20 | PXD031516 | Pride
Mouse Targeteed Shotgun Zinc 
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TranscriptomicsCharacterization of Calprotectin treated medium
The goal of this study is to correlate the transcriptional response of S. aureus cells grown in Calprotectin treated medium with that of cells grown in Mn or Zn depletion conditions. Keywords: RNA sample Staphylcoccus aureus strain Newman was grown to mid-log phase in Calprotectin treated medium or ...
ORGANISM(S): Staphylococcus aureus subsp. aureus str. Newman 
2010-05-26 | E-GEOD-9828 | biostudies-arrayexpress
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