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ProteomicsQuantitative proteomics of the infectious and replicative forms of Chlamydia trachomatis L2
The obligate intracellular developmental cycle of Chlamydia trachomatis presents significant challenges in defining its proteome. In this study we have app...
...d at 48h PI. We then used two-dimensional reverse phase UPLC to fractionate RB or EB peptides before mass spectroscopic analysis, providing absolute amount estimates of chlamydial proteins.
ORGANISM(S): Chlamydia Trachomatis Serovar L2 (strain 434/bu / Atcc Vr-902b) 
2016-06-28 | PXD003025 | Pride
L2 Reticulate body Chlamydia trachomatis Elementary body 
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ProteomicsMetabolic changes in adaptation to biofilm growth by streptococcus pneumoniae
Comparative analyses of protein expression between log-phase planktonic and 1-day and 7-day biofilm cultures from Streptococcus pneumoniae representing nascent and late phase biofilm growth were performed using the proteomic approach iTRAQ
ORGANISM(S): Streptococcus Pneumoniae Sp14-bs69 
2014-09-10 | PXD001182 | Pride
Biofilm Streptococcus pneumoniae 
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GenomicsSardiNIA Medical Sequencing Discovery Project

The SardiNIA Medical Sequencing Discovery Project is a study of the genetics of blood lipid levels and personality in a Sardinian population cohort. The project will generate draft genome sequences for 1,000 individuals using whole genome shotgun sequencing. The draft sequences will allow investiga...

phs000313.v3.p2 | EGA
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ProteomicsModulation of the tumor promoting functions of cancer associated fibroblasts by PDE5 inhibition
Modulation of the tumor promoting functions of cancer associated fibroblasts by PDE5 inhibition increases the efficacy of chemotherapy in human preclinical models of edophageal adenocarcinoma
ORGANISM(S): Homo Sapiens (human) 
2022-08-12 | PXD031148 | Pride
Lc-ms Proteomics Tmt 
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UnknownLoss of a histidine residue at the active site of S-locus ribonuclease is associated with self-compatibility in Lycopersicon peruvianum.
Not available
S-EPMC44232 | biostudies-other
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MetabolomicsAntiviral metabolite 3'-Deoxy-3',4'-didehydro-cytidine is detectable in serum and identifies acute viral infections including COVID-19

<strong>BACKGROUND: There is a critical need for rapid viral infection diagnostics to enable prompt case identification in pandemic settings and support targeted antimicrobial prescribing.

METHODS: Using untargeted high-resolution liquid chromatography coupled with m...

2022-02-10 | MTBLS718 | MetaboLights
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MetabolomicsAssessing the impact of nitrogen supplementation in oats across multiple growth locations and years with targeted phenotyping and high-resolution metabolite profiling approaches
Oats (Avena sativa L.) are a healthy food, being high in dietary fibre (e.g. β-glucans), antioxidants, minerals, and vitamins. Understanding the effect of variety and crop management on nutritional quality is important. The response of four oat varieties to increased nitrogen levels was investigated ...
2021-04-26 | MTBLS1801 | MetaboLights
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UnknownOn the pivotal role of PPAR? in adaptation of the heart to hypoxia and why fat in the diet increases hypoxic injury.
Not available
S-EPMC5072355 | biostudies-literature
0
GenomicsNational Institute on Aging (NIA) SardiNIA Study

Sardinia is the second largest island in the Mediterranean and constitutes a genetically isolated founder...
...s include anthropomorphic measures, plasma and serum markers (including cholesterol and other markers of cardiovascular disease), and personality traits (using the five-factor model).

The main goal of the study is to examine phenotypic similarities between relatives that yield information on the overall contributions of genes to trait variability. Data given here provide p-values for 98 traits studied in 1,412 individuals, based on genotyping with the Affymetrix 500K chip and imputed markers using the HapMap population as a reference (N=2,259,179). Sharing this genome assessment data at high level of resolution for a variety of quantitative traits will be useful for other groups to validate newly observed associations and to investigate possible pleiotropic effects.

For ulterior information, and in particular for any individual...

phs000338.v1.p1 | EGA
0
UnknownDirect evidence of generation and accumulation of β-sheet-rich prion protein in scrapie-infected neuroblastoma cells with human IgG1 antibody specific for β-form prion protein.
Not available
S-EPMC3340157 | biostudies-literature
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