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ProteomicsGu-Ben-Fang-Xiao decoction ameliorates airway remodeling by regulating the PI3K/AKT signaling pathway mediated by RTN4 in a chronic remission asthma murine model
...cularly for airway remodeling. Herein, developing alternative and more effective therapy to attenuate remodeling is worthy of further study. Gu-Ben-Fang-Xiao Decoction (GBFXD) has been used to treat asthma for decades effectively and safely. In present study, GBFXD significantly regulated the airway inf...
ORGANISM(S): Mus Musculus (mouse) 
2021-09-09 | PXD020711 | Pride
Airway remodeling Chronic remission asthma Gu-ben-fang-xiao decoction Rtn4 Pi3k/akt pathway 
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ProteomicsA label-free proteomics method to investigate the protective effect of Gu-Ben-Fang-Xiao in a chronic persistent murine asthma model
Ethnopharmacological relevance: Gubenfangxiao decoction (GBFXD) is a traditional Chinese medicine formula derived from Yupingfensan, an ancient formula widely used to treat respiratory diseases such as repeated respiratory infection, allergic rhinitis, bronchitis, and asthma. In recent years, GBFXD has ...
ORGANISM(S): Mus Musculus (mouse) 
2019-09-26 | PXD013244 | Pride
Gubenfangxiao decoction immune response chronic persistent asthma label-free proteomic inflammatory response Gubenfangxiao decoction  chronic persistent asthma  label-free proteomic  inflammatory response  immune response 
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UnknownXiao-Yin-Fang Therapy Alleviates Psoriasis-like Skin Inflammation Through Suppressing γδT17 Cell Polarization.
Not available
S-EPMC8087247 | biostudies-literature
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ProteomicsIdentification of whole-cell dsRNA-binding proteins by phase separation
...We also found that the ARM (armadillo/beta-catenin-like repeats) motif is a previously unknown dsRNA-binding domain, as demonstrated by biochemical experiments. Collectively, this study provides a useful approach for dsRBP identification and the discovery of a global dsRNA-binding proteome to compre...
ORGANISM(S): Sus Scrofa Domesticus (domestic Pig) 
2024-10-17 | PXD048971 | Pride
Armadillo/beta-catenin-like repeats Dsrna-binding proteome Dsrna-binding protein capture Dsrna-binding domain Dsrna-binding proteins 
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ProteomicsErastin induced protein expression change in H1975 cells
H1975 cells were treated with DMSO and erastin, respectively. Protein was extracted and separated using SDS-PAGE electrophoresis. MS analysis was performed and protein was identified and quantified using Proteome Discoverer™ 1.3 software using the SEQUEST® search engine.
ORGANISM(S): Homo Sapiens (human) 
2021-09-09 | PXD020205 | Pride
Lung cancer Erastin Ferroptosis 
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UnknownGu-Ben-Fang-Xiao Decoction Ameliorated Murine Asthma in Remission Stage by Modulating Microbiota-Acetate-Tregs Axis.
Not available
S-EPMC7212778 | biostudies-literature
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ProteomicsTranscriptome-wide Identification of Single-stranded RNA Binding Proteins
sinle-stranded RNA binding proteins were identified using DIA MS with the asist of RNA seconderay structure specific probe
ORGANISM(S): Homo Sapiens (human) 
2023-05-10 | PXD038757 | Pride
Transcriptome-wide Rna Dia 
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ProteomicsDiagnosis of T-cell-mediated kidney rejection by biopsy-based proteomic biomarkers and machine learning
...reproducibility of traditional histologic methods. Methods: Quantitative label-free mass spectrometry analysis was performed on a set of formalin-fixed, paraffin-embedded (FFPE) biopsies from renal transplant patients, comprising five biopsies with the diagnosis of T-cell-mediated rejection (TCMR),...
ORGANISM(S): Homo Sapiens (human) 
2023-02-01 | PXD038601 | Pride
Biomarker Quantitative proteomics Ffpe Machine learning Diagnosis Mass spectrometry Kidney transplantation 
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ProteomicsProtein profiles of ACUTE liver injury in mice mediated by CCl4 or APAP
Mice were treated with CCl4,APAP or olive oil for 24 h, protein changes were detected by mass spectrometry
ORGANISM(S): Mus Musculus (mouse) 
2024-10-05 | PXD029204 | Pride
Acute liver Mouse Mass spectrometry 
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UnknowniTRAQ-Based Proteomics Reveals Gu-Ben-Fang-Xiao Decoction Alleviates Airway Remodeling via Reducing Extracellular Matrix Deposition in a Murine Model of Chronic Remission Asthma.
Not available
S-EPMC8237094 | biostudies-literature
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