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The proteome of human brain synapses is highly complex and mutated in over 130 diseases. This complexity arose from two whole genome duplications early in the vertebrate lineage. Zebrafish are used in modelling human diseases, however its synapse proteome is uncharacterised and whether the teleost-spe...
ORGANISM(S): Danio Rerio (zebrafish) (brachydanio Rerio) Mus Musculus (mouse) 
2017-03-06 | PXD005630 | Pride
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Plants are often challenged by numerous biotic and abiotic environmental stresses. They have evolved efficient signaling networ...
...as higher levels of salicylic acid (SA) and reactive oxygen species (ROS), which are related with stomatal movement. The specific function of MPK4 in guard cells is unknown. In order to understand MPK4 functions in guard cells, it is essential to investigate MPK4-associated protein complex. Here we focus on identification of guard cell specific MPK4 complex using affinity purification following by mass spectrometry (AP-MS). Potential substrates were selected and validated with yeast two hybrid (Y2H).
ORGANISM(S): Arabidopsis Thaliana (mouse-ear Cress) 
2024-04-30 | PXD034347 | Pride
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The novel Coronavirus SARS-CoV-2 causes a respiratory illness called COVID-19 leading to a pandemic. An effective preventive vaccine against this virus is urgently needed.
ORGANISM(S): Severe Acute Respiratory Syndrome Coronavirus 2 
2020-07-30 | PXD020653 |
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