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ProteomicsLarge scale profiling of the physiological impact of a potent anti-cancer agent inhibiting early protein maturation
Fumagillin and its derivatives are therapeutically-useful compounds for their capacity to reduce cancer progression. Fumagillin exerts a specific proliferation inhibition on endothelial cell lines and on several tumor lines. The specific molecular target of fumagillin is MetAP2, one of the two cytoso...
ORGANISM(S): Homo Sapiens (human) 
2017-01-02 | PXD002690 | Pride
methionine aminopeptidase Co-translational modifications n-myristoyltransferase n-α-acetyltransferase n-terminal processing drug evaluation Co-translational modifications  n-terminal processing  methionine aminopeptidase  n-α-acetyltransferase  n-myristoyltransferase  drug evaluation 
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UnknownmTert induction in p21-positive cells counteracts capillary rarefaction and pulmonary emphysema
Not available
S-SCDT-10_1038-S44319-023-00041-1 | biostudies-other
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