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ProteomicsImmune surveillance of brain metastatic cancer cells is mediated by IFITM1 (Proteins identified in the >100 kDa fraction of conditioned media from all four cell lines)
The protein(s) larger than 100 kDa in conditioned medium from lung cancer cell lines activated microglia. The >100 kDa fraction of conditioned medium from H460, H1299, H2030, or H292 cells was collected. Proteins present in the conditioned medium were analyzed by LC-MS/MS.
ORGANISM(S): Homo Sapiens (human) 
2023-02-17 | PXD038129 | Pride
Brain metastatic colonization In vivo pooled genome-wide loss-of-function genetic screen Non-small cell lung cancer Interferon-induced transmembrane protein 1 (ifitm1) 
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ProteomicsImmune surveillance of brain metastatic cancer cells is mediated by IFITM1 (The coimmunoprecipitated proteins associated with the endogenous membrane IFITM1 of H1299 cells after IFNγ stimulation)
To examine the molecular basis of IFITM1 function, we performed a coimmunoprecipitation (co-IP) assay of cell membrane proteins followed by mass spectrometry analysis.
ORGANISM(S): Homo Sapiens (human) 
2023-02-17 | PXD038130 | Pride
Brain metastatic colonization In vivo pooled genome-wide loss-of-function genetic screen Non-small cell lung cancer Interferon-induced transmembrane protein 1 (ifitm1) 
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