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ProteomicsNeddylation is a global orchestrator of the molecular network driving Schwann cell myelination
Axonal myelination is essential for neuronal function and health. In peripheral nerves, deficient myelination is responsible for the morbidity of various forms of inherited or acquired neuropathies, including Charcot-Marie-Tooth disease and diabetic neuropathy. Decades of research have uncovered a co...
ORGANISM(S): Rattus Norvegicus (rat) 
2024-06-16 | PXD043917 | Pride
Ubiquitin-like Schwann cells Neddylation Label free Ptms 
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TranscriptomicsThe RNA-binding protein HuR coordinates global changes in gene expression during patterning of early peripheral nerves
Identify mRNA targets of the RNA-binding protein HuR in vivo during Schwann cell development using RIP-chip analysis. IP protocol of endogenous mRNA-transfected HuR complexes was performed as described in Keene et al. (2006). In brief, 500 mg of whole-cell lysate obtained from a pool of NB or P5 scia...
ORGANISM(S): Mus musculus 
2012-01-19 | E-MEXP-3519 | biostudies-arrayexpress
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