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E-GEOD-21681

ABSTRACT: Gene expression profile in three regions of the hippocampus of middle aged and old rats exposed to dietary restriction

OTHER RELATED OMICS DATASETS IN: PRJNA125839

PROVIDER: E-GEOD-21681 | ExpressionAtlas | 2015-09-15

REPOSITORIES: ExpressionAtlas

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Dataset's files

Source:

			Action	DRS
	E-GEOD-21681-analysis-methods.tsv	Tabular
	E-GEOD-21681-atlasExperimentSummary.Rdata	Rdata
	E-GEOD-21681-configuration.xml	Xml
	E-GEOD-21681-percentile-ranks.tsv	Tabular
	E-GEOD-21681.condensed-sdrf.tsv	Tabular

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Project description:Aging is associated with a decline in hippocampal mediated learning and memory, a process which can be ameliorated by dietary (caloric) restriction. We used Affymetrix gene expression analysis to monitor changes in three regions of the hippocampus (CA1, CA3, DG) of middle aged (18 months) and old (28 month) rats that were exposed to dietary restriction. Old rats were determined to be good performers (GP) or poor performers (PP) in behavioural tests to assess their hippocampal function. We used Affymetrix gene expression analysis to monitor changes in three regions of the hippocampus (CA1, CA3, DG) of middle aged (18 months) and old (28 month) rats that were exposed to dietary restriction.

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