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E-MTAB-10068

ABSTRACT: RNA-Seq of zebrafish whole-eye comparing wild-type and mab21l1 c.107delA p.(Lys36Argfs*7) embryos at 5 days post fertilization

PROVIDER: E-MTAB-10068 | ExpressionAtlas | 2023-06-15

REPOSITORIES: ExpressionAtlas

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Dataset's files

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			Action	DRS
	E-MTAB-10068-analysis-methods.tsv	Tabular
	E-MTAB-10068-analytics.tsv	Tabular
	E-MTAB-10068-atlasExperimentSummary.Rdata	Rdata
	E-MTAB-10068-configuration.xml	Xml
	E-MTAB-10068-g2_g1-mvaPlot.png	Other

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RNA-Seq of zebrafish whole-eye comparing wild-type and mab21l1 c.107delA p.(Lys36Argfs*7) embryos at 5 days post fertilization

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Project description:Currently there is little knowledge on the functions and signaling pathways of MAB21L1. Therefore, we developed a zebrafish genetic model of mab21l1 deficiency to use in order to gain insight into possibly affected pathways and transcripts. We conducted RNA-seq on zebrafish whole eyes which were dissected out at 5 days post fertilization. Three biological replicates per genotype (wild-type or homozygous mab21l1-c.107delA) were collected, with 50 eyes per replicate. RNA was extracted and purified and submitted to Macrogen to conduct RNA-Sequencing procedure.

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