Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

E-MTAB-2863

ABSTRACT: Transcription profiling by array of CD11C+ splenic dendritic cells from young (8 weeks) and old (110 weeks) mice treated with Poly I:C for 4 hours

PROVIDER: E-MTAB-2863 | ExpressionAtlas | 2014-10-10

REPOSITORIES: ExpressionAtlas

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	E-MTAB-2863-analysis-methods.tsv	Tabular
	E-MTAB-2863-atlasExperimentSummary.Rdata	Rdata
	E-MTAB-2863-configuration.xml	Xml
	E-MTAB-2863-percentile-ranks.tsv	Tabular
	E-MTAB-2863.condensed-sdrf.tsv	Tabular

Items per page:

1 - 5 of 33

Similar Datasets

Comparison of young (8 weeks) and aged (110 weeks) CD11C+ splenic dendritic cells from C57BL/6 mice

Project description:Total RNA was isolated from FACS purified CD11c+ splenic DC populations isolated from young (8 weeks old, n=3) and aged (110 weeks old, n=3) mice, that had been injected with Poly I:C for 4h previously. Microarray analysis was performed with the Affymetrix GeneChip Mouse Genome 430 2.0 Arrays. The arrays were hybridized, washed and scanned according to the standard Affymetrix protocol. The gene chip tests were performed by professional staff of Shanghai Biochip Company, PRC. Gene expression profiles and functional gene set enrichment analysis demonstrate that DC isolated aged mice are impaired in their ability to activate Natural Killer (NK) cells. The study is submitted for publication in June 2014.

2014-08-27 | E-MTAB-2863 | biostudies-arrayexpress

E-MTAB-5952

Project description:RNAseq of whole ovarian follicles from young and old mice.

2024-02-27 | E-MTAB-5952 | ExpressionAtlas

E-MTAB-7178

Project description:RNA sequencing of gamma-delta T cell subsets from young and old mice

2019-01-16 | E-MTAB-7178 | ExpressionAtlas

E-MEXP-1504

Project description:Transcription profiling by array of liver, lung, spleen and kidney from young and old mice.

2014-08-16 | E-MEXP-1504 | ExpressionAtlas

E-GEOD-4332

Project description:Transcription profiling by array of long-term haematopoietic stem cells from old and young mice

2014-07-03 | E-GEOD-4332 | ExpressionAtlas

E-GEOD-35322

Project description:Expression data from tail skin in young (5 months) and old (30 months) CB6F1 mice

2015-09-22 | E-GEOD-35322 | ExpressionAtlas

E-MTAB-5172

Project description:RNA-seq of 5 populations from the regenerative region of the brain of young and old mice

2019-05-14 | E-MTAB-5172 | ExpressionAtlas

Aging-triggered iron-rich insoluble protein aggregates in the spleen originate chiefly from red pulp macrophages.

Project description:Both iron homeostasis and erythropoiesis are known to be affected by aging. Iron needs in mammals are met primarily by iron recycling from senescent red blood cells (RBCs), a task chiefly accomplished by red pulp macrophages (RPMs) in the spleen. Given that RPMs continuously process iron, their cellular functions might be susceptible to age-dependent decline, a possibility that has been unexplored to date. In our project, we identified a formation of undegradable iron- and heme-rich extracellular aggregates in the spleens of 10-11-month-old female mice. To better understand the origin of these aggregates, here, we performed: i) protein identification and intrasample quantification (iBAQ) of proteins of magnetically-isolated red pulp macrophages from spleens of two female 8-weeks-old C57BL/6J (maintained on a standard diet) and ii) label-free quantification of proteins of the splenic protein aggregates formed in the mouse spleen 24 hours after intraperitoneal iron dextran injection, using dextran-injected mice as a control. Two 8-week-old C57BL/6J mice per group were analyzed. This dataset is related to the project PXD032900, which describes quanytitative analysis of proteins in aggregates magnetically isolated from spleen of aged (standard or iron-reduced diet) and young mice (standard diet).

2023-02-02 | PXD038660 | Pride

E-MTAB-7595

Project description:RNA-seq of heart tissue from 15 day old mice 4 hours post MycER activation compared to wild type controls. RNA-seq of heart tissues from adult mice that have expressed oncogenic H-Ras for 4 weeks followed by MycER activation for 4 hours compared to MycER negative controls.

2019-08-07 | E-MTAB-7595 | ExpressionAtlas

E-GEOD-59928

Project description:Expression data from 24 hours of Sox17 overexpression in pancreatic islets of a 16-week old mice

2015-07-29 | E-GEOD-59928 | ExpressionAtlas