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E-MTAB-5311

ABSTRACT: RNA-seq of Lewis lung carcinoma tumors in mice with or without exercise

PROVIDER: E-MTAB-5311 | ExpressionAtlas | 2019-05-14

REPOSITORIES: ExpressionAtlas

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			Action	DRS
	E-MTAB-5311-analysis-methods.tsv	Tabular
	E-MTAB-5311-analytics.tsv	Tabular
	E-MTAB-5311-atlasExperimentSummary.Rdata	Rdata
	E-MTAB-5311-configuration.xml	Xml
	E-MTAB-5311-g2_g1-mvaPlot.png	Other

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RNA-seq of Lewis lung carcinoma tumors in mice with or without exercise

Project description:Exercise has been correlated with retardation of tumor initiation and progression. However, it is unclear what are the molecular mechanisms behind this beneficial effect of exercise. In this study, we obtained RNA-seq data from biopsies of Lewis lung carcinoma tumors in a total of 16 mice, 8 with access to running wheel and 8 without (controls).

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RNA-seq of Lewis lung carcinoma tumors in mice with or without exercise

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Project description:Exercise has been correlated with prevention of weight loss (cachexia) attributed to tumor initiation and progression. However, it is unclear what are the molecular mechanisms behind this beneficial effect of exercise to prevent cachexia. In this study, we obtained RNA-seq data from biopsies of muscle in 24 mice with Lewis lung carcinoma that reached 1 cm3 volume, 14 with access to running wheel and 10 without (controls).

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